Excision of a mediastinal parathyroid gland with use of video-assisted thoracoscopy, intraoperative 99mTc-sestamibi scanning, and intraoperative monitoring of intact parathyroid hormone.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Roderick M QuirosRichard A Prinz

Abstract

To report the complementary use of video-assisted thoracoscopic surgery (VATS) and intraoperative 99mTc-sestamibi scanning for persistent secondary hyperparathyroidism due to a mediastinal supernumerary parathyroid gland. We describe a patient with recurrent secondary hyperparathyroidism attributable to a mediastinal parathyroid gland who underwent parathyroidectomy with use of VATS, intraoperative 99mTc-sestamibi scanning (gamma probe), and intraoperative monitoring of intact parathyroid hormone (iPTH). A 32-year-old man with chronic renal failure who had undergone a 4-gland parathyroidectomy with autotransplantation 14 years previously presented with symptomatic hypercalcemia. A preoperative single-photon emission computed tomographic (SPECT) sestamibi scan revealed a focus of mediastinal uptake, suggestive of an intrathymic gland. The patient underwent a cervical exploration, and the previously reimplanted parathyroid gland and the thymus were resected. iPTH levels failed to normalize, and the operation was terminated. A repeated SPECT scan again revealed an area of mediastinal uptake. Computed tomographic scan of the chest showed a mediastinal gland adjacent to the aortic arch. VATS and intra-operative sestamibi scanning ai...Continue Reading

References

Nov 1, 1991·Mayo Clinic Proceedings·R T SchlinkertR Argueta
Jan 1, 1995·The Annals of Thoracic Surgery·W R SmytheL R Kaiser
Dec 1, 1996·The British Journal of Surgery·P GullstrandO Mårtensson
Jul 1, 1997·The Annals of Thoracic Surgery·K OhnoS Yamamoto
Nov 14, 1997·Journal of the American College of Surgeons·R KnightJ T Moore
Oct 2, 1998·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·P MiccoliC Marcocci
Mar 23, 1999·The Annals of Thoracic Surgery·T KidoT Takao
Jun 12, 1999·The European Journal of Surgery = Acta Chirurgica·T Lesser, M Bartel
Nov 28, 2001·The Annals of Thoracic Surgery·M C OttR Reid
Aug 7, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Jacquelyn K O'HerrinHerbert Chen

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Citations

May 25, 2005·Annals of Nuclear Medicine·Vani Vijayakumar, Matthew E Anderson
Jun 28, 2011·Diabetes Technology & Therapeutics·Stuart LittlePhilip Home
May 28, 2008·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Andrew W ChaeMichael Bouvet

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