Excision of Nonpalpable Breast Cancer with Indocyanine Green Fluorescence-Guided Occult Lesion Localization (IFOLL).

Breast Care
Fatih AydoganVarol Celik

Abstract

BACKGROUND: Currently employed techniques for the localization of nonpalpable breast lesions suffer from various limitations. In this paper, we report on 2 patients in order to introduce an alternative technique, indocyanine green fluorescence-guided occult lesion localization (IFOLL), and determine its applicability for the surgical removal of this type of breast lesions. CASE REPORTS: Preoperatively, one of the patients had a needle biopsy-proven diagnosis of breast cancer, and the other one had suspicious findings for malignancy. Lesion localization was performed within 1 h before surgery under ultrasonography control by injecting 2 ml and 0.2 ml of indocyanine green into the lesion and its subcutaneous tissue projection, respectively. During surgery, the site of skin incision and the resection margins were identified by observing the area of indocyanine-derived fluorescence under the guidance of a near-infrared-sensitive camera. In both cases, the breast lesion was correctly localized, and the area of fluorescence corresponded well to the site of the lesions. Subsequent surgical excision was successful with no complications. On histopathologic examination, the surgical margins were found to be clear. CONCLUSION: IFOLL see...Continue Reading

Citations

Dec 7, 2013·Expert Review of Medical Devices·Fatih AydoganHalit Yilmaz
May 28, 2014·Journal of Surgical Oncology·Marc ThillJana Barinoff
Nov 14, 2015·Scientific Reports·Ryan P JudySunil Singhal
Sep 24, 2015·Journal of Surgical Oncology·Colleen M O'Kelly PriddyJulie E Lang
Oct 21, 2016·World Journal of Surgical Oncology·Jintao LiuMeng Tong
Jan 30, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·Sabas Carlos VieiraMarcus Luciano Lopes de Paiva Crisanto
Mar 6, 2018·Bulletin of Experimental Biology and Medicine·A L AkopovM A Magruk
Jan 29, 2020·The Breast Journal·Sarah FranciniMartha Duraes

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