PMID: 2108785Feb 26, 1990Paper

Excitatory effects of thyrotropin-releasing hormone (TRH) in hypoglossal motoneurons

Brain Research
J C Rekling

Abstract

The effect of thyrotropin-releasing hormone (TRH) was studied in 30 hypoglossal motoneurons from brainstem slices of guinea pigs. Bath application of TRH resulted in an increase of the spontaneous excitatory synaptic activity, depolarization of the neurons, increase of the input resistance and change of the duration of the falling phase of excitatory postsynaptic potentials. The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance.

References

Sep 23, 1985·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·T Takahashi
Oct 29, 1980·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R A NicollC E Jahr

❮ Previous
Next ❯

Citations

Feb 3, 2009·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·B L DaviesB E Taylor
Jan 4, 1998·Respiration Physiology·D A BaylissA J Berger
Mar 21, 2000·Respiration Physiology·R L Horner
Jun 1, 1996·The European Journal of Neuroscience·M Atzori, A Nistri
Aug 21, 1995·The Journal of Comparative Neurology·S M MurphyI J Llewellyn-Smith
Aug 15, 1993·The Journal of Comparative Neurology·S Manaker, L J Tischler
Oct 6, 2005·Respiratory Physiology & Neurobiology·Margaret T T Wong-Riley, Qiuli Liu
Apr 4, 2000·Physiological Reviews·J C ReklingJ L Feldman

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.