Executive dysfunction in Turkish children at high risk for schizophrenia.

European Child & Adolescent Psychiatry
Nese Perdahli FisYanki Yazgan

Abstract

To explore different aspects of executive function (i.e. sequencing, set shifting and mental flexibility) in children who are at high risk for schizophrenia by comparing them with normal controls. The high risk (HR) group consisted of 30 children whose parents were diagnosed as schizophrenia. As the control group (CG) 30 children, whose parents did not meet any DSM IV diagnostic criteria for any psychiatric disorder, participated. They were age and sex matched with the HR group. For the evaluation of different domains of cognitive functions Wechsler intelligence scale for children-revised (WISC-R), and a group of neuropsychological tests, including Trail Making A-B Tests, Color Form Test, and Progressive Figures Test were administered. Behavioral problems were assessed using Hacettepe Adjustment Scale. The subjects in the high risk group had significantly lower scores on Trail Making A-B, Color Form, Progressive Figures Tests, as well as subtests and scores of WISC-R (Information, Comprehension, Similarities, Picture Completion, Block Design, Object Assembly and Coding subtests, Verbal, Performance and Full Scale IQ scores). There is no significant difference between the two groups in the frequency and severity of behavioral pr...Continue Reading

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Citations

Oct 17, 2013·PloS One·Kim H W VerweijUNKNOWN Genetic Risk and Outcome in Psychosis (GROUP) investigators
Oct 13, 2012·International Review of Psychiatry·Prabha S ChandraVidyendran Rudhran
Jul 26, 2011·Brain and Cognition·Sarah C JacobsonHugh Garavan
Sep 10, 2010·Schizophrenia Research·Nikolaos KoutsoulerisEva M Meisenzahl
Oct 31, 2015·Schizophrenia Research·Juan P Borda, Louis A Sass
Aug 12, 2016·PloS One·Ana González-PintoUNKNOWN PEPs Group
Nov 20, 2008·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Marieke E AltinkJan K Buitelaar

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