Executive functioning deficits among adults with Bipolar Disorder (types I and II): A systematic review and meta-analysis

Journal of Affective Disorders
Tania DickinsonJacqui Coombes

Abstract

Executive functioning (EF) deficits contribute to a significant proportion of the burden of disease associated with bipolar disorder (BD). Yet, there is still debate in the literature regarding the exact profile of executive functioning in BD. The purpose of the present project was to assess whether EF deficits exist among adults suffering BD, and whether these deficits (if apparent) differ by BD subtype. A systematic search identified relevant literature. Randomised controlled trials that used neuropsychological assessment to investigate EF among adults 16-65 years) with a remitted DSM diagnosis of BD (type I or II) were included. Studies were published between 1994 and 2015. A systematic review and meta-analysis were undertaken. For individual studies, standardised mean differences (Cohen's d) and 95% confidence intervals were calculated and represented in forest plots to illustrate differences in executive performance between groups. Summary effects were produced and tests of heterogeneity employed to assess the dispersion and generalisability of results. Thirty-six studies met criteria for inclusion. Six domains of EF were identified: Set-shifting (SS), inhibition (INH), planning (PLA), verbal fluency (VF), working memory (...Continue Reading

Citations

Nov 15, 2017·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Hongyan RenTao Li
Feb 15, 2019·Expert Review of Neurotherapeutics·Trisha Chakrabarty, Lakshmi N Yatham
Jan 23, 2020·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Grant L IversonNoah D Silverberg
Sep 19, 2019·Applied Neuropsychology. Adult·Laura Damiani BrancoRochele Paz Fonseca
Jul 1, 2020·Psychological Medicine·Jennifer L BurgessR Hamish McAllister-Williams
Oct 14, 2017·International Journal of Bipolar Disorders·Dominik K E Beyer, Nadja Freund
Dec 10, 2020·Journal of Affective Disorders·Rodrigo B MansurRoger S McIntyre
Sep 11, 2019·Journal of Affective Disorders·Adam FijtmanMárcia Kauer-Sant'Anna
Oct 24, 2020·Journal of Dual Diagnosis·Enrique Moraleda-BarrenoJesús Gómez-Bujedo
Jan 8, 2021·International Journal of Geriatric Psychiatry·Elad OmerRamit Ravona-Springer
Apr 4, 2021·Brain Sciences·Gabriel G De la TorreSara González-Torre
Apr 18, 2021·Clinical Psychology Review·Amitai AbramovitchAvraham Schweiger
May 29, 2021·International Journal of Bipolar Disorders·Riccardo GuglielmoGregor Hasler
Aug 31, 2021·Frontiers in Neuroscience·Nina DalknerEva Z Reininghaus

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