Exercise and dietary advice intervention for survivors of triple-negative breast cancer: effects on body fat, physical function, quality of life, and adipokine profile

Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer
Anne K SwisherLinda Vona-Davis

Abstract

Regular exercise and healthy eating are routinely recommended for breast cancer survivors, and past studies show benefits in quality of life and decreased inflammation. However, this has not been tested specifically in triple-negative breast cancer survivors. Increasing physical activity and losing body fat are thought to positively affect inflammatory biomarkers that have been associated with breast cancer. Therefore, the primary purpose of this study was to determine if participation in an exercise and dietary counseling program can improve body fat, physical function, and quality of life in survivors of this aggressive breast cancer. Secondarily, we sought to determine if participation in the program had beneficial effects on obesity-related markers of the adipokine profile. Sixty-six survivors of triple-negative breast cancer with BMI >25 were invited to participate. Twenty-eight enrolled and 23 completed the randomized, controlled trial (13 intervention, 10 control). Moderate-intensity aerobic exercise (150 min per week, for 12 weeks) and diet counseling were compared to usual care, education only. The primary outcome of interest was weight loss (body mass, BMI, % fat), and secondary outcomes included physical function (ex...Continue Reading

References

Apr 9, 2004·The Journal of Clinical Endocrinology and Metabolism·Tongjian YouBarbara J Nicklas
Jul 20, 2007·Endocrine-related Cancer·Linda Vona-Davis, David P Rose
Feb 1, 2008·Nature Reviews. Cancer·Anne McTiernan
Dec 9, 2008·The Cancer Journal·Melinda L Irwin, Susan T Mayne
Jan 7, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Heather K NeilsonRobert C Millikan
Apr 30, 2009·Journal of the National Cancer Institute·Rachel Ballard-BarbashArthur Schatzkin
May 14, 2009·JAMA : the Journal of the American Medical Association·Miriam C MoreyWendy Demark-Wahnefried
May 28, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Brandon L PierceCornelia M Ulrich
Jun 13, 2009·Cytokine & Growth Factor Reviews·Linda Vona-Davis, David P Rose
Jul 25, 2009·Journal of Cancer Survivorship : Research and Practice·Rebecca N LatkaMelinda L Irwin
Aug 13, 2009·Expert Review of Anticancer Therapy·David P Rose, Linda Vona-Davis
Aug 19, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Stephanie M GeorgeRachel Ballard-Barbash
Dec 1, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Catherine DugganAnne McTiernan
Dec 27, 2011·Breast Cancer Research and Treatment·Christie A BefortCarol J Fabian
Apr 18, 2012·Cancer·Wendy Demark-WahnefriedSandra C Hayes
May 23, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lee W JonesMark Haykowsky
Feb 28, 2013·International Journal of Cancer. Journal International Du Cancer·Martina E SchmidtKaren Steindorf
Jul 25, 2014·Breast Cancer Research and Treatment·Stephanie M GeorgeRachel Ballard-Barbash
Sep 25, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Cari M KitaharaMeredith S Shiels

❮ Previous
Next ❯

Citations

Jul 18, 2015·Nutrients·Elena LionettiCarlo Catassi
Apr 24, 2015·Current Treatment Options in Oncology·Doris S M Chan, Teresa Norat
Jan 27, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Emily Cox-MartinDiane M Novy
Feb 2, 2018·The Cochrane Database of Systematic Reviews·Sarah KitsonEmma J Crosbie
May 17, 2018·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Dagmar HorakovaHelena Kollarova
Aug 25, 2017·The Cochrane Database of Systematic Reviews·Karis Kin Fong ChengWilson Wai San Tam
Jun 13, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jessica M ScottLee W Jones
Apr 15, 2018·Breast Cancer Research and Treatment·Frederico Soares FalcettaDaniela Dornelles Rosa
Sep 20, 2018·The Cochrane Database of Systematic Reviews·Rebecca R TurnerLiam Bourke
Nov 23, 2017·CA: a Cancer Journal for Clinicians·Wendy Demark-WahnefriedKaren Basen-Engquist
Aug 24, 2019·International Journal of Cancer. Journal International Du Cancer·Wendy Demark-WahnefriedHelen Krontiras
Nov 23, 2019·The Cochrane Database of Systematic Reviews·Sorrel BurdenChris Todd
Dec 20, 2018·The Proceedings of the Nutrition Society·Sorrel BurdenChris Todd
Feb 7, 2019·Frontiers in Oncology·Raheem J PaxtonKristen Allen-Watts
Jan 18, 2017·Journal of Cancer Survivorship : Research and Practice·Meeke HoedjesEllen Kampman
Nov 23, 2017·British Journal of Sports Medicine·Sarah E Neil-SztramkoKristin L Campbell
Dec 3, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Rowan T Chlebowski, Marina M Reeves
Dec 12, 2020·The Cochrane Database of Systematic Reviews·Hassan ShaikhJanette L Vardy
Dec 30, 2020·International Journal of Molecular Sciences·José Cesar Rosa-Neto, Loreana Sanches Silveira
Feb 12, 2021·Journal of the American College of Nutrition·Karina de J Diaz-Lopez, Graciela Caire-Juvera
Mar 21, 2021·Breast Cancer Research and Treatment·Patricia SheeanMelinda Stolley
Mar 20, 2021·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Tyler J BruinsmaKathleen M Sturgeon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Cancer: BRCA1 & BRCA2

Mutations involving BRCA1, found on chromosome 17, and BRCA2, found on chromosome 13, increase the risk for specific cancers, such as breast cancer. Discover the last research on breast cancer BRCA1 and BRCA2 here.

Breast Cancer Triple-N

Breast cancer cells have receptors for estrogen, progesterone, HER2 receptors (also called ERBB2). Triple-negative breast cancers do not have any of these receptors. Here are the latest discoveries pertaining to triple-negative breast cancers.

Breast Cancer: Therapeutic Approaches

Several different therapeutic approaches are used to treat breast cancer. These include chemotherapy, hormonal therapy, targeted therapy, and Immunotherapy. Discover the latest research on breast cancer therapeutic approaches here.