Exercise and non-pharmacological treatment of POTS

Autonomic Neuroscience : Basic & Clinical
Qi Fu, Benjamin D Levine

Abstract

Recent research has demonstrated that cardiovascular deconditioning (i.e., cardiac atrophy and hypovolemia) contributes significantly to the Postural Orthostatic Tachycardia Syndrome (POTS) and its functional disability. Therefore, physical reconditioning with exercise training and volume expansion via increased salt and fluid intake should be initiated early in the course of treatment for patients with POTS if possible. The use of horizontal exercise (e.g., rowing, swimming, recumbent bike, etc.) at the beginning is a critical strategy, allowing patients to exercise while avoiding the upright posture that elicits their POTS symptoms. As patients become increasingly fit, the duration and intensity of exercise should be progressively increased, and upright exercise can be gradually added as tolerated. Supervised training is preferable to maximize functional capacity. Other non-pharmacological interventions, which include: 1) chronic volume expansion via sleeping in the head-up position; 2) reduction in venous pooling during orthostasis by lower body compression garments extending at least to the xiphoid or with an abdominal binder; and 3) physical countermeasure maneuvers, such as squeezing a rubber ball, leg crossing, muscle pu...Continue Reading

Associated Clinical Trials

Citations

Jan 31, 2019·Scandinavian Journal of Medicine & Science in Sports·Päivi OksanenAntti M Kiviniemi
Aug 15, 2019·Annual Review of Medicine·Philip L Mar, Satish R Raj
Jul 17, 2020·Journal of the American Heart Association·Amanda J Miller, Kate M Bourne
Jul 17, 2020·Journal of the American Heart Association·Emily C SmithLuis E Okamoto
Aug 19, 2020·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Ravindra GaneshJohn K DiBaise
Jan 7, 2020·The Journal of the American Osteopathic Association·Bernadette Riley
Nov 30, 2018·Congenital Heart Disease·Camden L HebsonDavid W Hannon
Nov 4, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Yixi TuPhilip L Mar
Jan 23, 2021·Journal of the American College of Cardiology·David G Benditt, Richard Sutton
Jan 23, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Christopher H GibbonsRoy Freeman
Dec 22, 2020·Autonomic Neuroscience : Basic & Clinical·Alice LoughnanStephen James
Sep 7, 2020·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Mitchell G MiglisLauren Stiles
Apr 2, 2021·Annals of the American Thoracic Society·Rubabin ToobaAdriano R Tonelli
Jul 16, 2021·Autonomic Neuroscience : Basic & Clinical·Nicholas W LarsenMitchell G Miglis
Aug 26, 2021·Occupational Therapy in Health Care·Alexa Herrera, Joanna Behm
Oct 15, 2021·Occupational Therapy in Health Care·Asha VasThomas Parsons
Nov 13, 2021·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Christopher J MathiasAlan Hakim
Nov 19, 2021·American Journal of Physical Medicine & Rehabilitation·Amanda K MorrowLaura A Malone

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.