Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Martijn A SpruitEmiel Wouters

Abstract

Although lung cancer is a highly prevalent type of cancer, the effects of an inpatient multidisciplinary rehabilitation program on pulmonary function and exercise capacity have never been studied in these patients. Pulmonary function, 6-min walking distance and peak exercise capacity of 10 patients with a severely impaired pulmonary function following treatment of lung cancer were assessed in this pilot study before and after an 8-week inpatient multidisciplinary rehabilitation program. At baseline, patients had a restrictive pulmonary function and an apparent exercise intolerance (median 6-min walking distance: 63.6% predicted; median peak cycling load: 58.5% predicted). Despite the lack of change in median pulmonary function [FEV1: -0.01L, p = 0.5469], functional exercise capacity [145 m; 43.2% of the initial values, p=0.0020] and peak exercise capacity [26 W; 34.4% of the initial values, p = 0.0078] improved significantly compared to baseline. Future trials have to corroborate the present findings. Nevertheless, patients with lung cancer have a clear indication to start a comprehensive rehabilitation program following intensive treatment of their disease. In fact, based on the results of the present pilot study it appears th...Continue Reading

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References

Mar 1, 1990·The American Review of Respiratory Disease·S Foster, H M Thomas
Mar 1, 1996·American Journal of Respiratory and Critical Care Medicine·R GosselinkM Decramer
May 6, 1999·American Journal of Respiratory and Critical Care Medicine·R MejiaD A Mahler
Oct 9, 1999·The European Respiratory Journal·T TroostersM Decramer
Jul 11, 2002·The European Respiratory Journal·M A SpruitM Decramer
Mar 5, 2004·Patient Education and Counseling·Martijn A SpruitRik Gosselink
Feb 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Daniel A Galvão, Robert U Newton
Apr 20, 2005·Journal international de bioéthique = International journal of bioethics·UNKNOWN World Medical Association General Assembly
Jun 1, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ruud KnolsGeert Aufdemkampe
Jul 21, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Kathryn H SchmitzRobert Kane
Sep 6, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Antonio BobbioDario Olivieri

❮ Previous
Next ❯

Citations

May 28, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Sevgi OzalevliAtilla Akkoclu
Aug 29, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Hendrik Riesenberg, Andreas Stephan Lübbe
Jun 11, 2009·Current Oncology Reports·Lee W JonesAnil A Joy
Mar 8, 2011·American Journal of Clinical Oncology·Georg P GlattkiDionisios Spyratos
Jun 10, 2010·Current Opinion in Pulmonary Medicine·Vickie R Shannon
Apr 21, 2012·Current Opinion in Supportive and Palliative Care·Graeme J KoelwynNeil D Eves
Feb 5, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Elliot J CoupsJamie S Ostroff
Jan 25, 2013·Multidisciplinary Respiratory Medicine·Dewi Nurul MakhabahNicolino Ambrosino
Jun 30, 2009·The Tohoku Journal of Experimental Medicine·Hitoshi KagayaTakanobu Shioya
Mar 29, 2012·Sports Medicine·Charlotte N Steins BisschopAnne M May
Jun 7, 2012·Current Oncology·M GrossmanG Batist
Sep 2, 2011·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Esra PehlivanHulya Nilgun Gurses
Oct 17, 2013·American Journal of Respiratory and Critical Care Medicine·Martijn A SpruitUNKNOWN ATS/ERS Task Force on Pulmonary Rehabilitation
May 23, 2014·Archivos de bronconeumología·María Rosa Güell RousUNKNOWN Sociedad Española de Neumología y Cirugía Torácica (SEPAR)
Jun 15, 2007·Journal of Cardiopulmonary Rehabilitation and Prevention·Roberto P Benzo
Aug 8, 2008·Current Opinion in Supportive and Palliative Care·Elizabeth A Laude, Sam H Ahmedzai
Apr 14, 2010·Expert Review of Respiratory Medicine·Peter J Mazzone
Jan 15, 2011·Acta Oncologica·Andreas H AndersenAnders Mellemgaard
Dec 15, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jos A StigtHarry J M Groen
Apr 2, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Brett C BadeGerard A Silvestri
Aug 30, 2011·PM & R : the Journal of Injury, Function, and Rehabilitation·Mark E Huang, James A Sliwa
May 31, 2014·Clinics in Chest Medicine·Carolyn L RochesterRebecca H Crouch
Jan 16, 2013·Revue des maladies respiratoires·F VandenbosJ Mouroux
Jan 1, 2011·Seminars in Thoracic and Cardiovascular Surgery·Gonzalo VarelaEsther Ballesteros
Aug 6, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Morten QuistLis Adamsen
Feb 15, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·C L GrangerL Denehy
Sep 14, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·C Granger, L Denehy
Sep 25, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Lee W JonesDora Il'yasova
May 14, 2010·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Jamie S OstroffBernard J Park
May 2, 2009·Archives of Physical Medicine and Rehabilitation·G Stephen MorrisVickie R Shannon
Nov 21, 2007·Seminars in Oncology Nursing·Stacey Young-McCaughan, Sonya M Arzola
Nov 21, 2007·Seminars in Oncology Nursing·Carolyn Ingram, Constance Visovsky

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