Exercise capacity in different stages of hypertension in spontaneously hypertensive rats

The Journal of Sports Medicine and Physical Fitness
Helton O CamposCândido C Coimbra

Abstract

The aim of the present study was to investigate the exercise capacity of hypertensive rats at different stages of development of hypertension and to determine the most suitable index to evaluate the exercise capacity in different strains. Male spontaneously hypertensive rat (SHR) and normotensive wistar rats (NWR) of 5, 8, 12 and 16 weeks were submitted to the exercise capacity test. The exercise running time was measured and the workload was calculated. Normotensive and hypertensive rats when assess the exercise capacity by exercise running time exhibited a reduction in exercise performance over time. Moreover, hypertensive rats showed lower exercise capacity compared to normotensive control when analyzed by workload. In conclusion, the present results indicate that hypertensive rats exhibit reduced exercise capacity compared to normotensive rats regardless of age assessed. Besides that in experiments with strains with different body mass the most reliable index to assess exercise capacity is workload.

References

Dec 1, 1978·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·G A Brooks, T P White
Apr 1, 1982·Physiological Reviews·B Folkow
Mar 1, 1981·Circulation Research·N C Trippodo, E D Frohlich
Oct 9, 1998·Cardiovascular Research·S A Doggrell, L Brown
Mar 10, 1999·The American Journal of Physiology·S K BortolottoG M Stephenson
May 19, 2000·Neuroscience and Biobehavioral Reviews·L P Spear
Jun 1, 2000·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·K L De AngelisM C Irigoyen
Aug 8, 2001·Circulation·B I LevyH A Struijker-Boudier
Apr 3, 2002·Annals of Internal Medicine·Seamus P WheltonJiang He
Apr 23, 2002·Hypertension·Paul MuntnerPaul K Whelton
May 16, 2003·JAMA : the Journal of the American Medical Association·Aram V ChobanianUNKNOWN National High Blood Pressure Education Program Coordinating Committee
Mar 1, 1963·Japanese Circulation Journal·K OKAMOTO, K AOKI
Nov 19, 2003·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Motoyuki IemitsuIwao Yamaguchi
Nov 25, 2003·International Journal of Experimental Pathology·Robson Francisco CarvalhoMaeli Dal Pai-Silva
Mar 6, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Peter M KangSeigo Izumo
Apr 13, 2004·Medicine and Science in Sports and Exercise·Linda S PescatelloUNKNOWN American College of Sports Medicine
Jun 29, 2004·Pharmacology, Biochemistry, and Behavior·D D SoaresU Marubayashi
Dec 13, 2005·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Manabu KokuboToyoaki Murohara
Oct 25, 2006·Hypertension·François FeihlBernard I Levy
Jan 26, 2007·Neuroscience Letters·Thales N Prímola-GomesNilo R V Lima
Jun 25, 2009·Pharmacology, Biochemistry, and Behavior·Cláudio H BalthazarCândido C Coimbra
Sep 19, 2009·Journal of Atherosclerosis and Thrombosis·Fumiko NagatomoAkihiko Ishihara
Feb 2, 2010·Journal of the American College of Cardiology·Bryan Williams
Nov 5, 2010·Scandinavian Journal of Medicine & Science in Sports·R Meeusen, B Roelands
Apr 3, 2012·International Journal of Cardiology·R L DamattoM P Okoshi
Feb 5, 2013·Journal of Molecular and Cellular Cardiology·Miguel Araujo Carneiro-JúniorAntonio José Natali
Apr 24, 2013·Hypertension·Robert D BrookUNKNOWN American Heart Association Professional Education Committee of the Council for High Blood Pressure Research, Council on Card
Apr 10, 2014·Comprehensive Physiology·Lars NyboMichael N Sawka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Klaus-Dieter SchlüterRui Manuel da Costa Rebelo
Arquivos brasileiros de cardiologia
Luis Henrique Lobo Silame GomesThales N Prímola-Gomes
International Journal of Molecular Sciences
Ching HuangShin-Da Lee
© 2021 Meta ULC. All rights reserved