Exercise echocardiography in postmenopausal hormone users with mild systemic hypertension

The American Journal of Cardiology
A PinesD Ayalon

Abstract

Rest and exercise echocardiography (at dynamic and isometric exercise) were performed in 30 postmenopausal women (aged 54 +/- 4 years) with borderline to mild hypertension. They were then divided into 2 groups: 17 women who started oral hormone replacement therapy (0.625 mg/day conjugated estrogens or 2 mg/day estradiol) and a control group of 13 nonusers. After 6 to 9 months, a second echocardiography was performed in 26 women (4 withdrew). There were only a few changes in values obtained in the 12 controls at the end of follow-up compared with baseline. Primarily, these changes included a slight decrease in systolic blood pressure at rest and on exercise. Several significant morphologic and hemodynamic alterations appeared in 14 hormone users. Left ventricular cavity dimensions and mass became smaller: mean end-diastolic diameter decreased from 45.9 +/- 3 mm at baseline to 44.4 +/- 3 mm at study termination (p = 0.007). The corresponding values for end-systolic diameter were 25.8 +/- 4 mm and 23.9 +/- 4 mm (p = 0.006); for left atrium diameter, it was 34.5 +/- 4 mm and 32.5 +/- 4 mm (p = 0.001); for left ventricular wall width, it was 19.9 +/- 2 mm and 19.3 +/- 2 mm (p = 0.02); for left ventricular mass, it was 197 +/- 28 g a...Continue Reading

References

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Citations

Nov 28, 2002·European Journal of Heart Failure·Stamatis AdamopoulosDimitrios Th Kremastinos
Nov 7, 2002·Current Hypertension Reports·Enrique Z FismanAmos Pines
Nov 23, 2011·European Journal of Applied Physiology·Hyun-Min ChoiJong-Kyung Kim
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Mar 16, 2002·Journal of Applied Physiology·Shawn G HayesMarc P Kaufman

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