Abstract
The authors assessed the cross-sectional association between intensity of exercise in later life and coronary heart disease risk factors and subclinical disease among 2,274 men and women, 65 years of age and older, who were participants in the Cardiovascular Health Study (CHS) during 1989-1990. Subjects were free of prior clinical cardiovascular disease or impairment of physical function. Exercise intensity was characterized as low, moderate, or high, based on highest intensity exercise reported over the 2 weeks prior to the CHS baseline examination. After adjustment for age, education, and postmenopausal hormone therapy (among women), there was an inverse dose-response relationship of exercise intensity with selected risk factors. By low, moderate, and high exercise intensity, respectively: fasting insulin-men, 15.6 microU/ml, 14.1 microU/ml, and 12.6 microU/ml, p for trend <0.001; women, 14.8 microU/ml, 13.8 microU/ml, and 12.0 microU/ml, p for trend = 0.01; serum fibrinogen-men, 316.2 mg/dl, 315.4 mg/dl, and 300.0 mg/dl, p for trend = 0.01; women, 327.3 mg/dl, 317.0 mg/dl, and 310.7 mg/dl, p for trend = 0.01; lower extremity arterial disease by percent with ankle-arm index <0.9-men, 18.3, 5.5, and 3.7, p for trend = 0.01; wo...Continue Reading
Citations
Apr 29, 2009·Archives of Internal Medicine·Dariush MozaffarianDavid Siscovick
Jan 25, 2012·Archives of Neurology·Susan M LandauWilliam J Jagust
Jun 10, 2003·Current Atherosclerosis Reports·Shari S Bassuk, JoAnn E Manson
Aug 21, 2013·Atherosclerosis·Bethany Barone GibbsKerry J Stewart
Oct 24, 2002·Managed Care Interface·Diane Giaquinta
Jul 13, 2000·Patient Education and Counseling·I Vuori
Dec 19, 2003·Journal of Clinical Epidemiology·Paula Diehr, Shirley A A Beresford
Apr 13, 2001·Journal of the American Geriatrics Society·G L BurkeUNKNOWN CHS Collaborative Research Group
Sep 14, 2000·Ethnicity & Health·S PudaricS E Johansson
Dec 17, 2008·American Journal of Epidemiology·Alain G BertoniDavid R Jacobs
Oct 18, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·T KostkaM Bonnefoy
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
Dec 4, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L DiPietro
Mar 29, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Karen Bandeen-RocheLinda P Fried
Feb 5, 2008·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Christine S RitchieRichard Allman
Jul 20, 2010·Psychosomatic Medicine·Willem J KopJohn S Gottdiener
Feb 6, 2002·Preventive Cardiology·T KostkaM Bonnefoy
Feb 23, 2011·Heart·Sithu WinRoy C Ziegelstein
Aug 6, 2008·Circulation·Dariush MozaffarianDavid Siscovick
Oct 15, 2011·Stroke; a Journal of Cerebral Circulation·Evan L ThackerDavid S Siscovick
Mar 10, 2012·Vascular Medicine·Kathryn A BrittonLuc Djoussé
Feb 16, 2012·Clinical Trials : Journal of the Society for Clinical Trials·Frederick L BrancatiUNKNOWN Look AHEAD Study Group
Jan 28, 2014·PloS One·Magdalena KwaśniewskaWojciech Drygas
May 26, 2004·Sports Medicine·Sean Carroll, Mike Dudfield
Dec 17, 2008·Women's Health·Rekha Mankad, Patricia J M Best
Jun 11, 2010·The American Journal of Clinical Nutrition·Luc DjousséKenneth J Mukamal
Jul 8, 2014·PloS One·Matteo CesariSandrine Andrieu
Apr 25, 2009·The Journal of Nutrition, Health & Aging·W C Stephen, I Janssen
Jan 26, 2016·Annals of Vascular Surgery·Arto HeikkiläPäivi Korhonen
Aug 16, 2011·Metabolism: Clinical and Experimental·Celeste M VinluanKai I Cheang
Feb 27, 2007·Annals of Epidemiology·Gina S LovasiBruce M Psaty
Jun 7, 2005·Journal of the American Geriatrics Society·Caroline S BlaumLinda P Fried
Feb 18, 2003·Journal of the American Geriatrics Society·Michael WeinerLinda P Fried
Jun 2, 2009·Journal of the American Geriatrics Society·Caroline S BlaumJeremy Walston
May 21, 2009·Journal of the American Geriatrics Society·Christine T CigolleCaroline S Blaum
Aug 31, 2007·Journal of the American Geriatrics Society·Sonia K MakhijaChristine S Ritchie
Apr 30, 2014·Acta Clinica Belgica·E SieliwonczykM Vandewoude
May 30, 2009·Preventive Cardiology·Erin D MichosWendy Post
Jan 9, 2008·Journal of the American Geriatrics Society·Karlijn J van StralenSusan R Heckbert
Jan 10, 2006·Journal of the American Geriatrics Society·Ian JanssenRobert Ross
Aug 18, 2010·Human Brain Mapping·April J HoPaul M Thompson
Nov 19, 2011·Journal of the American Geriatrics Society·Denise K HoustonStephen B Kritchevsky
Sep 17, 2013·Geriatrics & Gerontology International·Ying LiYasuto Sato
Mar 1, 2015·ESC Heart Failure·Ahmed AbdelmawgoudAli Ahmed
Nov 13, 2004·Preventive Medicine·Norbert SchmitzJoachim Kugler
Dec 27, 2005·The American Journal of Cardiology·David P Swain, Barry A Franklin
Mar 25, 2014·Neurobiology of Aging·Miranka WirthWilliam J Jagust
Feb 1, 2003·Journal of the American Geriatrics Society·Mary McGrae McDermottCheeling Chan
Oct 1, 2013·Atherosclerosis·Joseph A C DelaneyMatthew A Allison
May 20, 2014·Neuroscience·M N BraskieP M Thompson