PMID: 15233247Jul 6, 2004Paper

Exercise rehabilitation and skeletal muscle benefits in hemodialysis patients

Clinical Nephrology
A Deligiannis

Abstract

End-stage renal disease patients on hemodialysis (HD) are characterized by poor exercise tolerance and debilitation symptoms, despite advances in dialysis procedures and erythropoietin use. Specifically, the muscle strength and endurance are diminished, as result of skeletal muscle dysfunction and atrophy. These changes are presumed to be secondary to uremic toxins, anemia, malnutrition, deconditioning, neurohormonal insults and other disorders. Previous studies have shown that exercise training limits the pathophysiological changes that occur in HD patients, mainly regarding peripheral skeletal muscle. It is supported that significant peripheral adaptations to training occur, as evidenced by the improvement of muscle function. Especially, morphological and metabolic benefits in the skeletal muscles have been well-documented in HD patients following physical rehabilitation programs. Such beneficial adaptations increase endurance and muscle strength and contribute to improved work capacity. The better understanding of these adaptive mechanisms may allow for improved exercise training strategies in these patients.

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Related Papers

Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses
R M ColangeloD Kessler-Hartnett
Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Joel D KoppleRichard Casburi
© 2022 Meta ULC. All rights reserved