Exercise suppression of thermoregulatory thermogenesis in warm- and cold-acclimated rats

Canadian Journal of Physiology and Pharmacology
J ArnoldD Richard

Abstract

An evaluation was made of the effects of an acute exercise bout on nonshivering thermogenesis (NST) in cold-acclimated rats (4 degrees C for 6 weeks) and shivering thermogenesis in 24 degrees C-acclimated rats (24 degrees C for 6 weeks). Assessment techniques included indirect calorimetry during treadmill running and brown adipose tissue (BAT) mitochondrial guanosine diphosphate (GDP) binding immediately following a treadmill run. Calorimetric results for 24 degrees C-acclimated rats running at 4 degrees C indicated total substitution of shivering thermogenesis by exercise-derived heat. No difference in GDP-binding, an index of BAT nonshivering thermogenic activity, was observed between exercised and nonexercised 24 degrees C-acclimated rats. Calorimetric results for cold-acclimated rats running at 4 degrees C indicated a total suppression in the energy cost associated with NST, exercise-derived heat replacing or substituting for NST. Examining BAT properties in the exercised cold-acclimated rats revealed a significant 40% decrease in BAT mitochondrial GDP-binding. These results suggest that during running, metabolic heat due to the exercise totally replaces shivering in 24 degrees C-acclimated rats and totally replaces BAT non...Continue Reading

Citations

Jan 1, 1988·European Journal of Applied Physiology and Occupational Physiology·J LeBlanc, P Diamond
Aug 26, 2006·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Lobke M VaanholtG Henk Visser
May 1, 1990·Physiology & Behavior·C J Gordon
Feb 1, 1991·Physiology & Behavior·P IteyD Richard
Jun 1, 1996·Pharmacology, Biochemistry, and Behavior·J R Wilson, B A Howard
May 1, 1996·Comparative Biochemistry and Physiology. Part A, Physiology·T MäkinenR Hissa
Jun 28, 2011·Integrative and Comparative Biology·Murray M Humphries, Vincent Careau
Oct 29, 1993·Annals of the New York Academy of Sciences·D Richard
Aug 23, 2018·Frontiers in Endocrinology·André C CarpentierÉric E Turcotte
Dec 1, 2020·Temperature : Multidisciplinary Biomedical Journal·Roberto Refinetti
Jun 1, 1989·The American Journal of Physiology·J Eley, J Himms-Hagen
Jan 1, 1989·Progress in Lipid Research·J Himms-Hagen

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