PMID: 9448897Aug 1, 1997Paper

Exercise vascular responses in health and disease

Australian and New Zealand Journal of Medicine
H Thomson

Abstract

In normal subjects during exercise, there is vasoconstriction of non-exercise resistance vessels and an increase in blood pressure. We have investigated patients with vasovagal syncope with structurally normal hearts and patients with hypertrophic cardiomyopathy compared with normal controls and found a failure of vasoconstriction in both patients with vasovagal syncope and hypertrophic cardiomyopathy compared with normals and this has been associated with exercise hypotension. An association between exercise hypotension and sudden death has previously been reported in hypertrophic cardiomyopathy. We speculate that in patients with vasovagal syncope and structurally and electrically normal hearts, exercise hypotension is well tolerated, but in patients with structurally abnormal hearts, exercise hypotension can have catastrophic consequences.

References

Jun 1, 1989·The Journal of Physiology·J H MitchellR G Victor
Oct 1, 1988·The Journal of Clinical Investigation·R G VictorR L Nunnally
May 1, 1973·The Journal of Clinical Investigation·A L MarkP G Schmid
Jan 1, 1972·Acta Physiologica Scandinavica·W DeliusB G Wallin
Jun 1, 1980·The Journal of Clinical Investigation·J L WalkerM D Thames
Jun 1, 1994·British Heart Journal·J F SneddonM P Frenneaux
Oct 17, 1913·The Journal of Physiology·A Krogh, J Lindhard

❮ Previous
Next ❯

Citations

Feb 13, 2001·Annals of Epidemiology·M T RichardsonA S Leon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.