Exogenous Glutathione Enhances Mercury Tolerance by Inhibiting Mercury Entry into Plant Cells

Frontiers in Plant Science
Yeon-Ok KimHunseung Kang

Abstract

Despite the increasing understanding of the crucial roles of glutathione (GSH) in cellular defense against heavy metal stress as well as oxidative stress, little is known about the functional role of exogenous GSH in mercury (Hg) tolerance in plants. Here, we provide compelling evidence that GSH contributes to Hg tolerance in diverse plants. Exogenous GSH did not mitigate the toxicity of cadmium (Cd), copper (Cu), or zinc (Zn), whereas application of exogenous GSH significantly promoted Hg tolerance during seed germination and seedling growth of Arabidopsis thaliana, tobacco, and pepper. By contrast, addition of buthionine sulfoximine, an inhibitor of GSH biosynthesis, severely retarded seed germination and seedling growth of the plants in the presence of Hg. The effect of exogenous GSH on Hg specific tolerance was also evident in the presence of other heavy metals, such as Cd, Cu, and Zn, together with Hg. GSH treatment significantly decreased H2O2 and O2(-) levels and lipid peroxidation, but increased chlorophyll content in the presence of Hg. Importantly, GSH treatment resulted in significantly less accumulation of Hg in Arabidopsis plants, and thin layer chromatography and nuclear magnetic resonance analysis revealed that G...Continue Reading

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Citations

Sep 25, 2020·Plant Physiology and Biochemistry : PPB·Bishwajit Kumar Kushwaha, Vijay Pratap Singh
Apr 18, 2021·Environmental Science and Pollution Research International·Almas JahanMuhammad Tariq Javed
Apr 13, 2021·The Plant Journal : for Cell and Molecular Biology·Jianzhong HuHunseung Kang
Jun 11, 2021·Bulletin of Environmental Contamination and Toxicology·Ge-Zi LiGuo-Zhang Kang
Jul 31, 2021·Journal of Hazardous Materials·Keji WangTingxuan Li

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Methods Mentioned

BETA
transgenic
MDA
NMR

Software Mentioned

SIGMAPLOT
systat

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