Exogenous neural stem cell transplantation for cerebral ischemia

Neural Regeneration Research
Ling-Yi LiaoQiang Gao

Abstract

Cerebral ischemic injury is the main manifestation of stroke, and its incidence in stroke patients is 70-80%. Although ischemic stroke can be treated with tissue-type plasminogen activator, its time window of effectiveness is narrow. Therefore, the incidence of paralysis, hypoesthesia, aphasia, dysphagia, and cognitive impairment caused by cerebral ischemia is high. Nerve tissue regeneration can promote the recovery of the aforementioned dysfunction. Neural stem cells can participate in the reconstruction of the damaged nervous system and promote the recovery of nervous function during self-repair of damaged brain tissue. Neural stem cell transplantation for ischemic stroke has been a hot topic for more than 10 years. This review discusses the treatment of ischemic stroke with neural stem cells, as well as the mechanisms of their involvement in stroke treatment.

References

May 20, 1994·Science·C Lois, A Alvarez-Buylla
Nov 11, 1998·Nature Medicine·P S ErikssonF H Gage
Jun 2, 2000·Science·D L ClarkeJ Frisén
Apr 22, 2003·Nature Neuroscience·Alan CarletonPierre-Marie Lledo
Oct 21, 2004·Nature Neuroscience·A Denise R GarciaMichael V Sofroniew
Aug 27, 2005·Journal of Neurosurgery·Douglas KondziolkaJeffrey Teraoka
Sep 6, 2005·Bulletin of Experimental Biology and Medicine·S S RabinovichV Ya Taraban
May 23, 2006·Current Opinion in Neurobiology·Tadeusz Wieloch, Karoly Nikolich
Jul 6, 2007·Journal of the Neurological Sciences·Marco BacigaluppiDirk M Hermann
Nov 24, 2007·Cell and Tissue Research·Asuka MorizanePatrik Brundin
Feb 26, 2008·Cell·Chunmei ZhaoFred H Gage
Mar 8, 2008·Stroke; a Journal of Cerebral Circulation·Piotr WalczakJeff W M Bulte
Nov 7, 2008·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Cleber A TrujilloHenning Ulrich
Jan 28, 2009·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Pengbo ZhangQianyan Kang
Nov 6, 2009·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Lian LiMichael Chopp
Feb 12, 2010·Journal of Neurotrauma·Wolfram TetzlaffBrian K Kwon
Mar 2, 2010·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Hongwei YuJin Lianhong
Jun 10, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Vladimer DarsaliaZaal Kokaia
Oct 19, 2010·Current Opinion in Neurobiology·Mo Weng, Cheng-Yu Lee
Dec 16, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Joshua Y ChuaRaphael Guzman
Dec 24, 2010·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Pengbo ZhangMing Gao
Jan 29, 2011·Stroke; a Journal of Cerebral Circulation·Sean I SavitzUNKNOWN STEPS Participants
Feb 9, 2011·Nature Biotechnology·George S Mack
Mar 25, 2011·Developmental Psychobiology·Kevin G BathFrancis S Lee
May 4, 2011·Stem Cell Reviews and Reports·Kristien ReekmansPeter Ponsaerts
May 24, 2011·Journal of Communication Disorders·Randolph J Nudo
Nov 15, 2011·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Matthew B JensenSu-Chun Zhang
Mar 8, 2012·Current Pharmaceutical Design·Ilaria DecimoGuido Fumagalli
May 3, 2012·Protein & Cell·Jun YaoFred H Gage
Aug 16, 2012·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Chunlei TianZhixian Wan

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Citations

Jan 31, 2020·Neural Regeneration Research·Ya ZhengLi-Ming Cheng
Sep 18, 2020·International Journal of Molecular Sciences·Satoshi SudaKazumi Kimura
Aug 11, 2020·The International Journal of Neuroscience·Muge MolbayEmin Turkay Korgun
Aug 13, 2020·International Journal of Molecular Sciences·Joseph Wai-Hin LeungBenson Wui-Man Lau
Dec 16, 2020·Neural Regeneration Research·Zhong-Yue LvJing Liu
Dec 19, 2020·Biomedicines·Daria D NamestnikovaKonstantin N Yarygin
May 19, 2021·Nature Biomedical Engineering·Zachary W Wagoner, Weian Zhao
Jan 16, 2022·Translational Stroke Research·Tong ZhaoJianhong Zhu

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