Exosomes and CAFs: partners in crime.

Blood
Benedetta Apollonio, Alan G Ramsay

Abstract

In this issue of Blood, Paggetti et al present novel findings that chronic lymphocytic leukemia (CLL)-derived exosomes and their molecular cargo are actively transferred to stromal cells that reside in the lymphoid tumor microenvironment (TME), promoting the reprogramming of these cells into cancer-associated fibroblasts (CAFs).

References

Oct 6, 2006·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Jia RuanShahin Rafii
Apr 5, 2011·Proceedings of the National Academy of Sciences of the United States of America·Etienne MoussayDavid J Galas
Jul 11, 2014·Nature Reviews. Cancer·David W Scott, Randy D Gascoyne
Jul 30, 2014·The Journal of Experimental Medicine·Daniel ÖhlundDavid Tuveson
Feb 11, 2015·Seminars in Cell & Developmental Biology·Jason WebberAled Clayton

❮ Previous
Next ❯

Related Concepts

Related Feeds

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

Related Papers

Nursing Standard
Colin Parish
Nature Genetics
Mark J Daly, David Altshuler
Nature Reviews. Cancer
Teresa Villanueva
Health Services Journal
Melanie Print
© 2021 Meta ULC. All rights reserved