Expand the pharyngitis paradigm for adolescents and young adults

Annals of Internal Medicine
Robert M Centor

Abstract

Current guidelines and review articles emphasize that clinicians should consider group A beta-hemolytic streptococcus in the diagnosis and management of patients with acute pharyngitis. Recent data suggest that in adolescents and young adults (persons aged 15 to 24 years), Fusobacterium necrophorum causes endemic pharyngitis at a rate similar to that of group A beta-hemolytic streptococcus. On the basis of published epidemiologic data, F. necrophorum is estimated to cause the Lemierre syndrome-a life-threatening suppurative complication-at a higher incidence than that at which group A streptococcus causes acute rheumatic fever. Moreover, these estimates suggest greater morbidity and mortality from the Lemierre syndrome. The diagnostic paradigm for adolescent pharyngitis should therefore be expanded to consider F. necrophorum in addition to group A streptococcus. Expanding the pharyngitis paradigm will have several important implications. Further epidemiologic research is needed on both F. necrophorum pharyngitis (especially clinical presentation) and the Lemierre syndrome. Clinicians need reliable diagnostic techniques for F. necrophorum pharyngitis. In the meantime, adolescents and young adults who develop bacteremic symptoms ...Continue Reading

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Citations

May 9, 2012·Archives of Internal Medicine·Andrew M FineKenneth D Mandl
Aug 14, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S BankJ Prag
May 31, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Carl LlorJosep Maria Cots
May 21, 2014·Journal of General Internal Medicine·Jacqueline BotrosMark C Henderson
May 9, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T E KlugC Struve
Oct 22, 2011·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Sigrun ChrubasikFlorella Magora
Feb 15, 2013·The American Journal of Emergency Medicine·Water Valesky, Konstantinos Agoritsas
Feb 20, 2014·Pediatric Annals·Crystal DukeJoseph R Hageman
Jun 30, 2010·Developmental Medicine and Child Neurology·Basheer Peer Mohamed, Lucinda Carr
Nov 26, 2010·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Steffen BankJørgen Prag
Feb 7, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A JensenJ Prag
Feb 7, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·K HedinM Sundqvist
Jul 15, 2015·BMC Infectious Diseases·Helena BjörkMartin Sundqvist
Aug 10, 2016·Annals of Clinical Microbiology and Antimicrobials·Mustafa KolukirikBahar K Ince
Jul 15, 2011·Revista Do Instituto De Medicina Tropical De São Paulo·Marc Zac HandlerUriel Sandkovsky
Jun 26, 2017·The Journal of Infection·Joshua OsowickiSimon Dobson
Oct 15, 2013·British Journal of Nursing : BJN·Dorothy HawesSiba Prosad Paul
Feb 2, 2018·The Pediatric Infectious Disease Journal·Saloni P ShethBlaise Congeni
Jan 27, 2017·Journal of Clinical Microbiology·Tam T VanJennifer Dien Bard
Nov 16, 2018·JBJS Case Connector·John J ManganEric Levicoff
Jan 5, 2018·Infection & chemotherapy·Young Kyung YoonShin Woo Kim
Jun 17, 2015·The Nurse Practitioner·Susan D Ruppert, Vaunette P Fay
Sep 21, 2012·Scandinavian Journal of Infectious Diseases·Robert M Centor
Jan 3, 2018·BMC Infectious Diseases·Jon PallonKatarina Hedin
Oct 31, 2019·Case Reports in Infectious Diseases·Ryo YasuharaTakayoshi Yamanouchi
Sep 25, 2020·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Faris F BrkicDavid T Liu
May 7, 2011·Journal of Medical Microbiology·T WingfieldK M B Ajdukiewicz
Feb 24, 2011·Expert Review of Anti-infective Therapy·Gunnar Dahlén, Anders Ebenfelt
Nov 30, 2018·Journal of Clinical Microbiology·Tam T VanJennifer Dien Bard
Jun 17, 2011·The New England Journal of Medicine·Carl Llor
Dec 10, 2020·Praxis·Ursina GerberGian Flury
Mar 25, 2021·Journal of American College Health : J of ACH·Benjamin SilverbergWilliam D Rose
Jun 16, 2015·Annals of Internal Medicine·Robert M CentorKen B Waites
Jun 16, 2015·Annals of Internal Medicine·Robert M CentorKen B Waites
Jun 16, 2015·Annals of Internal Medicine·Jeffrey A Linder
Feb 17, 2015·Annals of Internal Medicine·Jeffrey A Linder

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