Expanded polytetrafluoroethylene reinforcement material in glaucoma drain surgery

Journal of Glaucoma
T JacobE Duzman

Abstract

To determine whether a synthetic material, expanded polytetrafluoroethylene (E-PTFE), can be used successfully as a reinforcement material over the tubes of glaucoma drainage implants. Patches of E-PTFE were sutured over the tubes of Baerveldt glaucoma drains implanted in the eyes of New Zealand white rabbits. Two material thicknesses were tested: 0.5 mm in four eyes and 0.25 mm in five eyes. Rabbit donor scleral patches were used in five eyes as the control. Total ocular health and intraocular pressure were monitored every 2 weeks after the procedure. Six months after implantation, the eyes were harvested and analyzed histologically. Two of the four eyes that received 0.5-mm thick E-PTFE patches showed some conjunctival melting over the anterior corners of the material close to the limbus. All five eyes that received 0.25-mm thick E-PTFE patches showed a healthy cellular wound healing response and no conjunctival melting. Cellular infiltration and collagen deposition in the E-PTFE materials showed integration of the patch material into the surrounding tissue. In the control eyes, marked thinning and resorption of the donor sclera immediately above the drainage tube was noted. Thin (0.25 mm) E-PTFE patches were well tolerated i...Continue Reading

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Citations

Jul 20, 2011·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Kentaro NishidaKohji Nishida
Dec 19, 2002·The British Journal of Ophthalmology·C KimB Ahn
May 14, 2011·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Aashish AnandCelso Tello
Dec 2, 2015·The Cochrane Database of Systematic Reviews·Xue WangAnne Coleman
Apr 15, 2006·Journal of Korean Medical Science·Hyeon Il LeeJae Chan Kim
Sep 1, 2012·Journal of Current Glaucoma Practice·Stirbu Oana, Jorge Vila

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