PMID: 11317462Apr 25, 2001Paper

Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications

Postgraduate Medicine
T M Ramahi

Abstract

The ARBs are a new class of drugs with broad therapeutic potential in cardiovascular disease. These agents act by selectively inhibiting the AT1 subtype of the angiotensin II receptors. They are effective antihypertensive agents with promise, theoretically, in the prevention and regression of ventricular hypertrophy. They are safe and well tolerated in patients with CHF and might be effective in improving survival and reducing morbidity. ARBs also might have a similar role in improving the clinical outcomes of patients with coronary artery disease and chronic nephropathy. Their precise role in the treatment and prevention of cardiovascular and renal disease should be established by several ongoing clinical trials.

References

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Citations

Oct 29, 2002·The American Journal of Medicine·Ernesto L Schiffrin
Mar 13, 2003·Mayo Clinic Proceedings·Prerana Manohar, Ileana L Piña
May 24, 2007·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Thomas E DeleaGerry Oster

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