Expanding analytic possibilities in pediatric solid organ transplantation through linkage of administrative and clinical registry databases

Pediatric Transplantation
Justin GodownJonathan H Soslow

Abstract

Database linkage is a common strategy to expand analytic possibilities. Our group recently completed a linkage between the SRTR and PHIS databases for pediatric heart transplant recipients. The aim of this project was to expand the linkage between SRTR and PHIS to include liver, kidney, lung, heart-lung, and small bowel transplants. All patients (<21 years) who underwent liver, kidney, lung, heart-lung, or small bowel transplant were identified from the PHIS database using APR-DRG codes (2002-2018). Linkage was performed in a stepwise approach using indirect identifiers. Hospital costs were estimated based on hospital charges and cost-to-charge ratios, inflated to 2018 dollars and described by transplant type. A total of 14 061 patients overlapped between databases. Of these, 13 388 (95.2%) were uniquely linked. Linkage success ranged from 92.6% to 97.8% by organ system. A total of 12 940 (92%) patients had complete cost data. Hospitalization costs were greatest for patients undergoing small bowel transplantation with a median cost of $734 454 (IQR $336 174 - $1 504 167), followed by heart $565 386 (IQR $352 813 - $999 216), heart-lung $471 573 (IQR $328 523 - 992 438), lung $303 536 (IQR $215 383 - $612 749), liver $200 448 (I...Continue Reading

References

Aug 15, 2014·Frontiers in Pediatrics·Tellen D BennettUNKNOWN Pediatric Acute Lung Injury and Sepsis Investigators (PALISI)
Sep 18, 2015·Cardiology in the Young·Sara K PasqualiRyan R Davies
Dec 30, 2016·World Journal for Pediatric & Congenital Heart Surgery·David F VenerSara K Pasquali
Jan 3, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M A SchnitzlerB L Kasiske
Jan 5, 2018·Pediatric Cardiology·Joshua D ChewJustin Godown
Apr 21, 2018·Transplantation·Justin GodownDebra A Dodd
Jan 24, 2019·The Journal of Thoracic and Cardiovascular Surgery·Son Q DuongBrian Feingold

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Citations

Jan 19, 2021·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Vikram K RaghuKenneth J Smith
Jan 25, 2020·Journal of Pediatric Gastroenterology and Nutrition·Sophoclis P AlexopoulosJustin Godown

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