Expanding the Concept of Translational Research: Making a Place for Environmental Health Sciences

Environmental Health Perspectives
Kristianna G PettiboneG W Collman

Abstract

The National Institute of Environmental Health Sciences (NIEHS) introduces a new translational research framework that builds upon previous biomedical models to create a more comprehensive and integrated environmental health paradigm. The framework was developed as a graphical construct that illustrates the complexity of designing, implementing, and tracking translational research in environmental health. We conceptualize translational research as a series of concentric rings and nodes, defining "translation" as movement either from one ring to another or between nodes on a ring. A "Fundamental Questions" ring expands upon the research described in other frameworks as "basic" to include three interrelated concepts critical to basic science research: research questions, experimental settings, and organisms. This feature enables us to capture more granularity and thus facilitates an approach for categorizing translational research and its growth over time. We anticipate that the framework will help researchers develop compelling long-term translational research stories and accelerate public health impacts by clearly mapping out opportunities for collaborations. By using this paradigm, researchers everywhere will be better positio...Continue Reading

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Citations

Aug 4, 2018·Environmental Health Perspectives·Gwen W CollmanLinda S Birnbaum
Apr 9, 2019·Environmental Health Perspectives·Joel D Kaufman, Cynthia L Curl
Mar 7, 2020·Environmental Health Perspectives·Joel D Kaufman
Jul 17, 2019·Public Health Nursing·Jessica CastnerBarbara Polivka
Jun 5, 2020·BMC Public Health·Marta SalgadoMónica Duarte Oliveira
Sep 11, 2020·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Matthew C Cave
Dec 3, 2020·Revista Da Sociedade Brasileira De Medicina Tropical·Naiane Araújo PatrícioAbrahão Fontes Baptista
Apr 4, 2021·International Journal of Environmental Research and Public Health·Jaime MadriganoLaura J Faherty
May 6, 2021·Journal of Clinical and Translational Science·Sara E DodsonWilliam M Trochim

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