Expanding the Potential of the Solvent-Assisted Method to Create Bio-Interfaces from Amphiphilic Block Copolymers.

Biomacromolecules
Stefano Di LeoneWolfgang Meier

Abstract

Artificial membranes, as materials with biomimetic properties, can be applied in various fields, such as drug screening or bio-sensing. The solvent-assisted method (SA) represents a straightforward method to prepare lipid solid-supported membranes. It overcomes the main limitations of established membrane preparation methods, such as Langmuir-Blodgett (LB) or vesicle fusion. However, it has not yet been applied to create artificial membranes based on amphiphilic block copolymers, despite their enhanced mechanical stability compared to lipid-based membranes and bio-compatible properties. Here, we applied the SA method on different amphiphilic di- and triblock poly(dimethylsiloxane)-block-poly(2-methyl-2-oxazoline) (PDMS-b-PMOXA) copolymers and optimized the conditions to prepare artificial membranes on a solid support. The real-time membrane formation, the morphology, and the mechanical properties have been evaluated by a combination of atomic force microscopy and quartz crystal microbalance. Then, selected biomolecules including complementary DNA strands and an artificial deallylase metalloenzyme (ADAse) were incorporated into these membranes relying on the biotin-streptavidin technology. DNA strands served to establish the cap...Continue Reading

References

Jun 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·O LivnahJ L Sussman
Feb 24, 2009·Biosensors & Bioelectronics·Karim El KiratKarsten Haupt
Apr 10, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Travers H AndersonJacob N Israelachvili
Mar 17, 2010·Microscopy Research and Technique·C CanaleS Dante
Apr 23, 2010·Biointerphases·Andreas O HohnerJoachim O Rädler
Jan 11, 2011·Macromolecular Bioscience·Jan DornWolfgang Meier
Feb 22, 2011·The European Physical Journal. E, Soft Matter·J-F Le MeinsS Lecommandoux
Sep 6, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Michael D DimitriouEdward J Kramer
Aug 7, 2012·Langmuir : the ACS Journal of Surfaces and Colloids·Karmena JaskiewiczAnja Kroeger
Mar 19, 2014·The Journal of Physical Chemistry. B·Goh Haw ZanNam-Joon Cho
Aug 12, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed R TabaeiNam-Joon Cho
Sep 11, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Camelia DraghiciCornelia G Palivan
Oct 7, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed R TabaeiNam-Joon Cho
Feb 14, 2015·Langmuir : the ACS Journal of Surfaces and Colloids·Seyed R TabaeiNam-Joon Cho
Feb 24, 2015·ACS Applied Materials & Interfaces·Christopher A R ChapmanErkin Seker
Sep 29, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Danielle MortonLuke Theogarajan
Nov 6, 2015·Physical Chemistry Chemical Physics : PCCP·Min Chul KimNam-Joon Cho
Nov 14, 2015·Chemical Society Reviews·Cornelia G PalivanWolfgang Meier
Dec 10, 2015·Journal of Visualized Experiments : JoVE·Seyed R TabaeiNam-Joon Cho
Jan 8, 2016·Physical Chemistry Chemical Physics : PCCP·Min Chul KimNam-Joon Cho
Aug 18, 2016·Physical Chemistry Chemical Physics : PCCP·Jurriaan J J GillissenNam-Joon Cho
Dec 28, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Kabir H BiswasNam-Joon Cho
Jun 8, 2018·Advanced Science·Serena RigoCornelia G Palivan
Jul 5, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Camelia DraghiciCornelia G Palivan
Aug 7, 2018·Chemical Science·Tillmann HeinischThomas R Ward
Sep 5, 2018·Chemical Society Reviews·Emeline RideauKatharina Landfester
Jan 24, 2019·Frontiers in Chemistry·Saziye Yorulmaz AvsarCornelia G Palivan
Feb 2, 2019·Current Opinion in Biotechnology·Andrea BelluatiCornelia G Palivan
Mar 4, 2019·Journal of Colloid and Interface Science·Yan-Ling YangHeng-Kwong Tsao
Mar 16, 2019·Biotechnology Advances·John H T LuongJeremy D Glennon
Jun 9, 2019·Nature Protocols·Abdul Rahim FerhanNam-Joon Cho
Aug 14, 2019·ACS Central Science·Holly J Davis, Thomas R Ward
Sep 12, 2019·Journal of the American Chemical Society·Shuke WuThomas R Ward
Dec 21, 2019·Nanoscale·Dalin WuCornelia G Palivan
Jan 29, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Joshua A Jackman, Nam-Joon Cho
May 10, 2020·The Journal of Physical Chemistry. B·Stefano Di LeoneWolfgang P Meier
Aug 15, 2020·Science·R Morris BullockYogesh Surendranath

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