Expanding the protein catalogue in the proteome reference map of human breast cancer cells

Proteomics
Ida Pucci-MinafraSalvatore Minafra

Abstract

In this report we present a catalogue of 162 proteins (including isoforms and variants) identified in a prototype of proteomic map of breast cancer cells. This work represents the prosecution of previous studies describing the protein complement of breast cancer cells of the line 8701-BC, which has been well characterized for several parameters, providing to be a useful model for the study of breast cancer-associated candidate biomarkers. In particular, 110 spots were identified ex novo by PMF, or validated following previous gel matching identification method; 30 were identified by N-terminal microsequencing and the remaining by gel matching with maps available from our former work. As a consequence of the expanded number of proteins, we have updated our previous classification extending the number of protein groups from 4 to 13. In order to facilitate comparative proteome studies of different kinds of breast cancers, in this report we provide the whole complement of proteins so far identified and grouped into the new classification. A consistent number of them were not described before in other proteomic maps of breast cancer cells or tissues, and therefore they represent a valuable contribution for breast cancer protein data...Continue Reading

References

Aug 1, 1989·British Journal of Cancer·S MinafraD E Woolley
Jun 1, 1994·International Journal of Cancer. Journal International Du Cancer·M PedrocchiC W Heizmann
Jan 1, 1993·Annual Review of Cell Biology·C Georgopoulos, W J Welch
Aug 1, 1993·The Journal of Cell Biology·M A Hill, P Gunning
Apr 1, 1996·Trends in Biochemical Sciences·B W Schäfer, C W Heizmann
Jan 1, 1996·Methods in Enzymology·W C BarkerD G George
Mar 1, 1996·Analytical Chemistry·A ShevchenkoM Mann
May 20, 1997·Molecular & General Genetics : MGG·F SladeczekF Le Bouffant
Jun 1, 1997·Cellular and Molecular Life Sciences : CMLS·K von der Mark, J Mollenhauer
Oct 6, 2000·Journal of the National Cancer Institute·C Jolly, R I Morimoto
Dec 2, 2000·Cell Proliferation·K HelmbrechtL Rensing
Feb 24, 2001·Results and Problems in Cell Differentiation·H Leffler
Oct 13, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·P Savagner
Oct 13, 2001·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·M J van HemertG P van Heusden
Dec 26, 2001·Nucleic Acids Research·Laurent FalquetAmos Bairoch
Dec 26, 2001·Nucleic Acids Research·Loredana Lo ConteAlexey G Murzin
Dec 26, 2001·Nucleic Acids Research·Alex BatemanErik L L Sonnhammer
Jan 30, 2002·Frontiers in Bioscience : a Journal and Virtual Library·Jiyun Kim, Katherine A Hajjar
Feb 2, 2002·Nature·Laura J van 't VeerStephen H Friend
Mar 28, 2002·Physiological Reviews·Volker Gerke, Stephen E Moss
Mar 30, 2002·The Journal of Biological Chemistry·Henrik J DitzelJens C Jensenius
Jul 4, 2002·Annals of the New York Academy of Sciences·Ida Pucci-MinafraSalvatore Minafra
Jul 19, 2002·Proteomics·Ida Pucci-MinafraSalvatore Minafra
Aug 15, 2002·Biochemical and Biophysical Research Communications·Xiao Qian Chen, Albert Cheung Hoi Yu
Sep 12, 2002·Biochimica Et Biophysica Acta·Fu-Tong LiuJohn L Wang
Sep 17, 2002·Briefings in Bioinformatics·Terri K Attwood
Dec 17, 2002·Cell Stress & Chaperones·Renu WadhwaSunil C Kaul
Dec 21, 2002·The Journal of Peptide Research : Official Journal of the American Peptide Society·B S ValléeF Schoentgen
Jan 9, 2003·The Lancet Oncology·John R BensonMitsuhiro Hayashi
Jan 10, 2003·Nucleic Acids Research·Hongzhan HuangCathy H Wu
Apr 16, 2003·Nature·Francis S CollinsUNKNOWN US National Human Genome Research Institute

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Citations

Apr 7, 2009·Journal of the American Society for Mass Spectrometry·Jenny M ArmentaIulia M Lazar
Oct 5, 2011·Genetics and Molecular Research : GMR·G G CostaE M S F Ribeiro
Jul 29, 2008·Connective Tissue Research·Ida Pucci-MinafraPatrizia Cancemi
Dec 17, 2009·Connective Tissue Research·Patrizia CancemiIda Pucci-Minafra
Feb 23, 2008·Connective Tissue Research·Ida Pucci-MinafraSalvatore Minafra
May 10, 2011·Journal of Pharmacological and Toxicological Methods·Hannah BatesonChris W Sutton
Aug 31, 2010·Leukemia Research·Luigi MinafraPatrizia Cancemi
Feb 28, 2008·Biochimica Et Biophysica Acta·Enrica EleuterioStefania Angelucci
Jan 1, 2009·Proteomics. Clinical Applications·Vaïk StrandeHubert Hondermarck
Jan 1, 2007·Proteomics. Clinical Applications·Ida Pucci-MinafraAntonio Marrazzo
May 30, 2012·Proteomics. Clinical Applications·Patrizia CancemiIda Pucci-Minafra
Jul 19, 2018·Oncotarget·Patrizia CancemiSalvatore Feo
Jan 4, 2019·Nature Communications·Xiaotian NiJun Qin
May 2, 2020·International Journal of Molecular Sciences·Miriam ButtacavoliPatrizia Cancemi
Feb 15, 2008·Journal of Proteome Research·Karen L AbbottMichael Pierce
Feb 21, 2008·Journal of Proteome Research·Ida Pucci-MinafraSalvatore Minafra
Mar 4, 2008·Journal of Proteome Research·Hubert HondermarckXuefen Le Bourhis
Jun 22, 2010·Journal of Proteome Research·Chris W SuttonKyriacos Kyriacou
Oct 16, 2007·Journal of Proteome Research·Simona FontanaGiacomo De Leo

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