Expansion of CD8+CD57+ T Cells in an Immunocompetent Patient with Acute Toxoplasmosis.

Advances in Hematology
R García-MuñozR Lecumberri

Abstract

CD57+ T cells increase in several viral infections like cytomegalovirus, herpesvirus, parvovirus, HIV and hepatitis C virus and are associated with several clinical conditions related to immune dysfunction and ageing. We report for the first time an expansion of CD8+ CD57+ T cells in a young patient with an acute infection with Toxoplasma gondii. Our report supports the concept that CD8+ CD57+ T cells could be important in the control of chronic phase of intracellular microorganisms and that the high numbers of these cells may reflect the continuing survey of the immune system, searching for parasite proliferation in the tissues.

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Citations

Mar 22, 2013·Science Translational Medicine·Simon ReinkeGeorg N Duda
Jun 30, 2011·Immunology·Marius StriogaDainius Characiejus
Jan 10, 2017·Frontiers in Immunology·Olga LourençoLuis Taborda-Barata

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Methods Mentioned

BETA
X-ray
enzyme-linked immunosorbent assay

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