PMID: 9436286Jan 1, 1997Paper

Expectant management as an option for men with stage T1c prostate cancer: a preliminary study

World Journal of Urology
J L MohlerJ A Freeman

Abstract

The outcome of patients selecting observation of clinical stage T1c prostate cancer is unknown. A total of 101 men with clinical stage T1c prostate cancer were evaluated, counseled, and monitored in a standard fashion. Altogether, 27 men who elected observation were older and had greater co-morbidity but similar tumor characteristics as compared with 74 men who elected radical prostatectomy. In all, 9 men demonstrated clinical or biochemical evidence of progression after a mean follow-up of 23 months; 4 men who underwent radical prostatectomy had specimen-confined disease and undetectable post-operative levels of PSA. Observation appears to be a viable option for some men with clinical stage T1c prostate cancer.

References

Sep 11, 1992·The Journal of Urology·W P McWhorterH J Eyre
Apr 22, 1992·JAMA : the Journal of the American Medical Association·J E JohanssonU B Krusemo
Apr 25, 1991·The New England Journal of Medicine·W J CatalonaG L Andriole
Feb 25, 1991·Cancer·W F WhitmoreI M Thompson
Sep 1, 1974·Journal of Chronic Diseases·M H Kaplan, A R Feinstein
Oct 1, 1984·The Journal of Urology·I M ThompsonC R Spence
Feb 2, 1994·JAMA : the Journal of the American Medical Association·J I EpsteinC B Brendler
Aug 23, 1995·JAMA : the Journal of the American Medical Association·P C AlbertsenJ Fine
Jun 16, 1993·Journal of the National Cancer Institute·T Reynolds
Jan 11, 1995·JAMA : the Journal of the American Medical Association·M S LitwinR H Brook
May 26, 1993·JAMA : the Journal of the American Medical Association·G L Lu-YaoJ E Wennberg
Jan 24, 1996·JAMA : the Journal of the American Medical Association·J A DuganJ E Oesterling

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Citations

Jun 29, 2000·Medical Oncology·S N PentyalaS A Khan
Feb 15, 2008·Der Urologe. Ausg. A·M GraefenH Huland
Sep 4, 2008·Current Urology Reports·Marc A Dall'Era, Christopher J Kane
Jul 17, 2007·The Journal of Urology·Christopher R GriffinWilliam J Catalona
Apr 22, 2008·BJU International·Jan Adolfsson
Feb 16, 2010·Urology·Marc Birkhahn, Richard J Cote
Jul 23, 2009·Deutsches Ärzteblatt International·Lothar Weissbach, Jens Altwein

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