Experience-dependent increases in sharp-wave ripples near visual targets

BioRxiv : the Preprint Server for Biology
Timothy K Leonard, Kari L Hoffman


We measured hippocampal sharp-wave ripples during goal-directed visual exploration in macaques. Exploratory sharp-wave ripples were more frequent on familiar trials, in the second half of search, and near the visual target (i.e., the goal location). These spatial and temporal properties may help SWRs coordinate hippocampal and extra-hippocampal firing sequences that guide actions based on past experiences.

Related Concepts

Spatial Distribution
Goal Directed Therapy
Clinical Trials
Macaca mulatta
Hippocampus (Brain)

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