Mar 1, 1976

Experience with a simple method for estrogen receptor assay in breast cancer

Clinica Chimica Acta; International Journal of Clinical Chemistry
L Liskowski, D P Rose

Abstract

A simple procedure for the assay of specific estrogen receptors in breast cancer tissue is described. Estrogen receptors were detected in 74% of primary tumors, 71% of skin metastases and 63% of lymph node metastases. Postmenopausal patients and younger oophorectomized women had estrogen receptor-containing tumors more frequently, and at higher levels, than uncastrated, premenopausal, patients. The stability of estrogen receptors was not affected by the transportation of samples from distant hospitals, providing that they were kept frozen in Tris buffer, pH 8.0, at all times.

  • References3
  • Citations8

References

Mentioned in this Paper

Malignant Neoplasm of Skin
Estrogen receptor alpha, human
Premenopausal Symptoms
Hormone Receptors, Cell Surface
Primary Neoplasm
Estradiol, (16 alpha,17 beta)-Isomer
Neoplasms
Menopause
Tromethamine
Secondary Malignant Neoplasm of Lymph Node

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