Experience with a simple method for estrogen receptor assay in breast cancer

Clinica Chimica Acta; International Journal of Clinical Chemistry
L Liskowski, D P Rose

Abstract

A simple procedure for the assay of specific estrogen receptors in breast cancer tissue is described. Estrogen receptors were detected in 74% of primary tumors, 71% of skin metastases and 63% of lymph node metastases. Postmenopausal patients and younger oophorectomized women had estrogen receptor-containing tumors more frequently, and at higher levels, than uncastrated, premenopausal, patients. The stability of estrogen receptors was not affected by the transportation of samples from distant hospitals, providing that they were kept frozen in Tris buffer, pH 8.0, at all times.

References

May 1, 1970·The Journal of Clinical Endocrinology and Metabolism·S G Korenman, B A Dukes
May 1, 1973·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·U SpaerenA Pihl

Citations

Oct 1, 1978·Journal of Steroid Biochemistry·A J KoendersT J Benraad
Jun 1, 1982·Journal of Steroid Biochemistry·M A de LarminatP S Rennie
Mar 1, 1980·The British Journal of Surgery·R A HawkinsA P Forrest

Related Concepts

Age Factors
Mammary Neoplasms, Human
Castration
Aerodiol
Estrogen Effect
Hydrogen-Ion Concentration
Lymphatic Metastasis
Mastectomy
Menopause
Neoplasm Metastasis

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