Experience with highly purified porcine factor VIII in a patient with haemophilia A and a factor VIII inhibitor

Clinical and Laboratory Haematology
B T ColvinC Buckley

Abstract

Highly purified porcine factor VIII has been advocated for the treatment of bleeding episodes in patients with haemophilia who have inhibitors to factor VIII. This approach has been successful in a patient with an intermediate potency inhibitor showing little cross-reactivity to porcine material. As in some other reported cases, a severe allergic reaction occurred on one occasion but did not preclude the subsequent use of the porcine concentrate in carefully controlled conditions.

References

Mar 27, 1982·Lancet·P HewittS J Machin
Jan 24, 1981·British Medical Journal·E E MayneT Ingles
Jun 20, 1981·British Medical Journal·J G Erskine, J F Davidson
Aug 1, 1981·British Medical Journal·P B Kernoff, E G Tuddenham

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