PMID: 9548344Apr 21, 1998Paper

Experience with pineal region tumors

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
J K KangM C Kim

Abstract

The results are reported of a retrospective review of the presentation and outcome of 43 pineal region tumors treated from 1982 to 1996, including 20 identified tumors: 5 germinomas, 8 teratomas, 2 embryonal carcinomas, 1 endodermal sinus tumor, 2 pineocytomas and 2 pineoblastomas. Of the 43 tumors reviewed, 36 were located in the pineal region, 5 in the suprasellar, and 2 in both the pineal and suprasellar regions. Twenty patients underwent surgical resection: total in 6 and partial in 10, while only a biopsy was taken in 4 cases. Fifteen patients were managed on the basis of serum CSF tumor markers and radiation response. Twenty-three patients with germinomas received radiotherapy (RT) and had a 5-year survival rate of 87%. Fifteen patients with non-germinomatous germ cell tumors received RT and chemotherapy following direct surgery, and 5 died (mortality rate of 33.3%). The overall survival rate of the 43 patients with pineal tumors was 79.1% (34/43) and the death rate was 20.9% (9/43). It is now recognized that the wide variety of tumor types found in the pineal region necessitates different modes of treatment, and improved microsurgical and stereotactic surgical techniques have made mortality and morbidity rates acceptably...Continue Reading

Citations

Jun 30, 2001·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·P ChiewvitS Suthipongchai
Mar 24, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Vicente CucciaGraciela Zuccaro
Nov 23, 2006·Journal of Neuro-oncology·D KeeneUNKNOWN Canadian Pediatric Brain Tumor Consortium
Apr 5, 2011·Neurosurgical Focus·Peter F MorgensternMark M Souweidane
Jun 19, 2012·Acta neurochirurgica·Sandro M KriegMichael Stoffel
Aug 8, 2015·Revista da Associação Médica Brasileira·Fernanda das Chagas Angelo Mendes TenorioÁlvaro Aguiar Coelho Teixeira
Mar 8, 2014·Arquivos de neuro-psiquiatria·Peng WangYan-Hui Liu
Dec 2, 2015·Oncology Letters·Florian BöhrnsenAngelika Gutenberg
Nov 21, 2015·Journal of Korean Neurosurgical Society·Jong Hoon ParkYoung Hyun Cho
Mar 3, 2018·Journal of Neurosurgery·Stepan FedorkoAndreas W Unterberg
Sep 18, 2002·Neurosurgery·Toshinori HasegawaL Dade Lunsford
Mar 3, 2010·Journal of Neurosurgery. Pediatrics·Edward S Ahn, Liliana Goumnerova
Nov 3, 2016·Journal of Neuro-oncology·Adam M SonabendJeffrey N Bruce
Jan 22, 2005·Cancer·Anil V ParwaniSyed Z Ali

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