PMID: 9175483Apr 1, 1997Paper

Experiences of epilepsy surgery in intractable seizures with past history of CNS infection

Yonsei Medical Journal
J H LeeK Huh

Abstract

We studied the clinical characteristics, location of epileptogenic regions, and the surgical outcomes in 18 patients with intractable epilepsy associated with previous CNS infections. All patients underwent an extensive presurgical evaluation and 11 patients had intracranial EEG monitoring. On the basis of presurgical evaluation, epileptic regions were localized to the mesial temporal (n = 12) and the neocortical (n = 6) regions. The age of the time of CNS infection was significantly younger and the latent period of non-febrile seizures after CNS infection was longer in patients with mesial temporal lobe epilepsy (MTLE). MRI showed hippocampal atrophy and hippocampal signal changes in 11 of 12 patients with MTLE. Among 6 patients with neocortical epilepsy (NE) 5 patients had normal MRI and one showed cerebral hemi-atrophy. Surgery was successful (class I & II) in all patients with MTLE, however, in the patients with neocortical epilepsy, seizure-free results were not achieved in any patients after resective surgery (6 patients) and only 2 patients achieved Class II outcomes after a second epilepsy surgery consisting of neocortical resection. Patients with MTLE after CNS infection were differentiated from the group of neocortica...Continue Reading

Citations

Aug 28, 1999·Journal of the Neurological Sciences·R L Kutsy
Jun 19, 2007·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Wang-Tso LeeWen-Yi Shau
Dec 17, 2009·Epilepsia·Kerry-Ann A StewartH Steve White
Sep 5, 2012·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J Sellner, E Trinka
Mar 30, 2010·Epilepsia·P S ChandraManjari Tripathi
Oct 6, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·M D HolmesL M Ojemann
Jul 13, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ricardo Silva CentenoSergio Cavalheiro
Aug 6, 2021·Epilepsy & Behavior : E&B·Jafar Mehvari HabibabadiNasim Tabrizi

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