Experimental and CFD flow studies in an intracranial aneurysm model with Newtonian and non-Newtonian fluids

Technology and Health Care : Official Journal of the European Society for Engineering and Medicine
S V FrolovAndrea Balasso

Abstract

According to the clinical data, flow conditions play a major role in the genesis of intracranial aneurysms. The disorder of the flow structure is the cause of damage of the inner layer of the vessel wall, which leads to the development of cerebral aneurysms. Knowledge of the alteration of the flow field in the aneurysm region is important for treatment. The aim is to study quantitatively the flow structure in an patient-specific aneurysm model of the internal carotid artery using both experimental and computational fluid dynamics (CFD) methods with Newtonian and non-Newtonian fluids. A patient-specific geometry of aneurysm of the internal carotid artery was used. Patient data was segmented and smoothed to obtain geometrical model. An elastic true-to-scale silicone model was created with stereolithography. For initial investigation of the blood flow, the flow was visualized by adding particles into the silicone model. The precise flow velocity measurements were done using 1D Laser Doppler Anemometer with a spatial resolution of 50 μ m and a temporal resolution of 1 ms. The local velocity measurements were done at a distance of 4 mm to each other. A fluid with non-Newtonian properties was used in the experiment. The CFD simulatio...Continue Reading

References

Jan 1, 1988·Heart and Vessels·H J SteigerH J Reulen
Jul 4, 2006·Journal of Biomechanical Engineering·Alvaro A ValenciaCristina H Amon
Dec 13, 2006·Journal of Biomechanical Engineering·Yiemeng HoiHui Meng
Apr 17, 2008·Journal of Biomechanical Engineering·Matthew D FordDavid A Steinman
Feb 2, 2012·Computer Methods in Biomechanics and Biomedical Engineering·Xiaohong Wang, Xiaoyang Li
Mar 29, 2012·Computational and Mathematical Methods in Medicine·Woowon Jeong, Kyehan Rhee
Mar 19, 2013·Computer Methods in Biomechanics and Biomedical Engineering·Kara L HallAmy T Neidhard-Doll
Apr 23, 2013·Annals of Biomedical Engineering·Trung B LeFotis Sotiropoulos
Nov 12, 2013·Bio-medical Materials and Engineering·Lifang WangGuifang Sun
Mar 13, 2014·Journal of Biomechanics·Valérie DeplanoEric Bertrand
Apr 29, 2014·Journal of Biomechanical Engineering·Victor L MarreroKenneth E Jansen
Oct 29, 2014·Annals of Biomedical Engineering·V L RayzM T Lawton
Dec 30, 2014·Journal of Biomechanics·Andrzej PolanczykIreneusz Zbicinski
Dec 31, 2014·Journal of Biomechanics·Ryo KoizumiTomoyuki Yambe

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Citations

Dec 7, 2019·Computer Methods in Biomechanics and Biomedical Engineering·Haoyao CaoTinghui Zheng
Jun 20, 2019·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Khalid M SaqrMakoto Ohta
May 20, 2020·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Khalid M Saqr
Jul 26, 2019·Biomedical Engineering Online·Sergey SindeevBenjamin Friedrich
Dec 14, 2018·Medical & Biological Engineering & Computing·Khalid M SaqrMakoto Ohta
Jun 3, 2020·Cardiovascular Engineering and Technology·Haoyao CaoTinghui Zheng
Nov 16, 2019·AJNR. American Journal of Neuroradiology·O BrinaM I Vargas
Dec 3, 2020·Cardiovascular Engineering and Technology·Qing-Zhuo ChiYu-Chen Jing

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