PMID: 6162522Feb 9, 1981Paper

Experimental and morphological studies of te noradrenaline innervations in the nucleus tractus spinalis nervi trigemini of the rat with special reference to their fine structures

Brain Research
E SenbaN Shimizu

Abstract

An attempt was made to elucidate the origins and fine structure of the noradrenaline (NA) terminals in the nucleus tractus spinalis nervi trigemini (Vsp) of the rat. The present study revealed that the NA in the Vsp is supplied from two NA neuron systems; bilateral locus coeruleus (LC) and medullary NA neuron group, on the grounds that: (1) two types of fluorescent fibers (fine and coarse) were identified in the Vsp; and (2) HRP injected in to the Vsp resulted in labeling of neurons of the bilateral LC and bulbal NA areas, particularly the ipsilateral A1 area. The fine structure of the NA terminals in the Vsp was investigated by a modified potassium permanganate fixation method. The NA terminals in this area contained a number of small cored vesicles together with a small number of large cored vesicles. The most frequent feature of the NA terminals found in this area wa axo-dendritic contact. A lesser, but still substantial, number with axo-axonic contact were also noticed, in connection with which, it should be stressed that the non-NA terminals examined in this study were always presynaptic in structure, since the clear vesicles found in the non-NA terminals sometimes aggregated close to the contact membrane, where some of th...Continue Reading

References

May 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·R SimantovS H Snyder
Jul 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·T HökfeltG Nilsson
May 1, 1977·Stroke; a Journal of Cerebral Circulation·T ItakuraN Shimizu
Apr 1, 1973·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·F E Bloom
Jan 1, 1967·Zeitschrift für Zellforschung und mikroskopische Anatomie·T Hökfelt
Jun 30, 1972·Science·J H LaVail, M M LaVail

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Citations

Jun 1, 1983·Neuroscience·T A Lovick, J H Wolstencroft
Dec 24, 1984·Brain Research·R L McBride, J Sutin
Jun 14, 2013·Journal of Psychopharmacology·Elemer Szabadi
Dec 1, 1987·Archives of Disease in Childhood·T Hertzberg, H Lagercrantz

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