Experimental autoimmune encephalomyelitis in the rat

Current Protocols in Immunology
R H Swanborg, J A Stepaniak

Abstract

This unit details the materials and methods required for both active induction and adoptive transfer of experimental autoimmune encephalomyelitis (EAE) in the SJL mouse strain using intact proteins or peptides from the two major myelin proteins: proteolipid protein (PLP) and myelin basic protein (MBP). Detailed materials and methods required for the purification of both PLP and MBP are also described. Modifications of the specified protocols may be necessary for efficient induction of active or adoptive EAE in other mouse strains.

References

Feb 1, 1992·European Journal of Immunology·D SunC Coleclough
Nov 1, 1991·Annals of Neurology·K SelmajA H Cross
Jan 1, 1988·Methods in Enzymology·R H Swanborg
Feb 1, 1989·European Journal of Immunology·J ChlubaJ T Epplen
Oct 1, 1995·Clinical Immunology and Immunopathology·R H Swanborg
Oct 1, 1994·Journal of Neuroimmunology·K E GouldR H Swanborg

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Citations

Nov 4, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Jordi EsparzaJoseph A Madri
Feb 15, 2008·Journal of Leukocyte Biology·Taba KheradmandRobert H Swanborg
Apr 24, 2018·Journal of Immunology Research·Xuemei QiuAiping Lu

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