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Experimental diarrhea in cynomolgus monkeys by oral administration with Clostridium perfringens type A viable cells or enterotoxin

Japanese Journal of Medical Science & Biology

Jun 1, 1975

Tetsuji UemuraSoichi Sakai

PMID: 525

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Abstract

Purified C. perfringens type A enterotoxin fed orally in an amount of 5 mg caused both vomiting and diarrhea in the monkey only when the gastric juice had been neutralized. Exposure of enterotoxin to pH 4.0 or below rapidly destroyed the activity. All three monkeys receiving sodium bica...read more

Mentioned in this Paper

Oral Cavity
Intestines
Platyrrhini
Clostridium perfringens
Monkeys
Sodium Bicarbonate
Gastric Juice
Intestinal Wall Tissue
Diarrhea
Macaca fascicularis
Paper Details
References
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    • Citations9
    • References12
    • Citations9
  • Experimental diarrhea in cynomolgus monkeys by oral administration with Clostridium perfringens type A viable cells or enterotoxin

    Japanese Journal of Medical Science & Biology

    Jun 1, 1975

    Tetsuji UemuraSoichi Sakai

    PMID: 525

    DOI:

    Abstract

    Purified C. perfringens type A enterotoxin fed orally in an amount of 5 mg caused both vomiting and diarrhea in the monkey only when the gastric juice had been neutralized. Exposure of enterotoxin to pH 4.0 or below rapidly destroyed the activity. All three monkeys receiving sodium bica...read more

    Mentioned in this Paper

    Oral Cavity
    Intestines
    Platyrrhini
    Clostridium perfringens
    Monkeys

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    Paper Details
    References
    • References12
    • Citations9
    • References12
    • Citations9
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