Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations

The ISME Journal
Richard E Lenski

Abstract

Evolution is an on-going process, and it can be studied experimentally in organisms with rapid generations. My team has maintained 12 populations of Escherichia coli in a simple laboratory environment for >25 years and 60 000 generations. We have quantified the dynamics of adaptation by natural selection, seen some of the populations diverge into stably coexisting ecotypes, described changes in the bacteria's mutation rate, observed the new ability to exploit a previously untapped carbon source, characterized the dynamics of genome evolution and used parallel evolution to identify the genetic targets of selection. I discuss what the future might hold for this particular experiment, briefly highlight some other microbial evolution experiments and suggest how the fields of experimental evolution and microbial ecology might intersect going forward.

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Citations

Mar 10, 2018·Evolution; International Journal of Organic Evolution·Joel SharbroughMaurine Neiman
Dec 2, 2017·Annals of the New York Academy of Sciences·Kristina Linnea Hillesland
Jun 9, 2018·Biotechnology Progress·Tharmala TharmalingamJennitte Stevens
Feb 13, 2018·Nature Ecology & Evolution·Lennart T BachUlf Riebesell
Mar 31, 2019·Biotechnology Journal·Roberto G StellaJulia Frunzke
Oct 24, 2019·Biochemical Society Transactions·David CoombesRenwick C J Dobson
Aug 23, 2019·Proceedings of the National Academy of Sciences of the United States of America·Nelson FrazãoIsabel Gordo
Aug 10, 2019·Journal of Evolutionary Biology·Debika Choudhury, Supreet Saini
Oct 30, 2019·The ISME Journal·Magdalena K StoevaJohn D Coates
Feb 16, 2020·Journal of Molecular Evolution·David A LiberlesAndrew Storfer
Mar 12, 2020·Journal of Molecular Evolution·Ľubomír Tomáška, Jozef Nosek
Nov 11, 2019·Applied and Environmental Microbiology·Patrick D Schloss
May 8, 2020·Letters in Applied Microbiology·T M Wassenaar, K Zimmermann
Sep 27, 2019·The Journal of Microbiology·Xianxing XieRuifu Yang
Sep 15, 2018·Journal of Experimental Botany·Julien NowakMaxime Pauwels
Feb 27, 2019·Environmental Microbiology·Misha G Mehta-KolteJohn D Coates
Jun 19, 2019·Nature Ecology & Evolution·Ember M MorrisseyBruce A Hungate
Jun 19, 2019·Nature Ecology & Evolution·Steven D Allison
Mar 12, 2020·Genome Biology and Evolution·Claire BurnyChristian Schlötterer
Aug 28, 2019·Annual Review of Marine Science·Sinéad CollinsMartina A Doblin
May 21, 2020·Royal Society Open Science·Anastasia V WassLouise J Johnson
Aug 12, 2020·Nature Ecology & Evolution·Troy E SandbergBernhard O Palsson
Jun 18, 2020·MSystems·Brittany A NiccumBenjamin E Wolfe
Aug 26, 2018·Nature Microbiology·David A Hutchins
Dec 15, 2018·Microbial Biotechnology·Morten H H Nørholm
Nov 10, 2018·Science·Zachary D BlountJonathan B Losos
Oct 20, 2019·International Journal of Environmental Research and Public Health·Lei ZhangJiahu Jiang
Nov 11, 2019·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Luciano Lopes QueirozGustavo Augusto Lacorte
Oct 10, 2020·Microbial Genomics·Kelle C FreelFlorence Arsène-Ploetze

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