PMID: 6540715Jan 1, 1984Paper

Experimental infection with Mycobacterium kansasii in athymic nude mice

Experimental Pathology
M KubínD Schlegerová

Abstract

Subcutaneous infection with Mycobacterium kansasii did not cause mortality in athymic nu/nu and control nu/+ mice. It had a stimulatory activity comparable to obligatory mycobacterial pathogens: thymus-dependent lymphatic tissues areas were populated during the infection by lymphocytes also in nu/nu mice in which a low degree of migration inhibition factor production could be seen. In both models of chief site of mycobacterial trapping and phagocytosis was the hyperplastic interdigitating cell mesh in the thymus-dependent areas of lymph nodes. A detailed morphological description of the organ changes is given.

References

Apr 1, 1978·Experimental Eye Research·H N FukuiJ H Kinoshita
Oct 1, 1977·Developmental and Comparative Immunology·F D WilsonR Graham
Jul 1, 1979·Cellular Immunology·A TagliabueJ L McCoy
Jul 1, 1981·The Journal of Experimental Medicine·M C NussenzweigZ A Cohn

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