PMID: 8972050Oct 1, 1996Paper

Experimental inoculation of foals and pigs with an enterotoxigenic E. coli isolated from a foal

Veterinary Microbiology
R E HollandR A Wilson

Abstract

Hemolytic E. coli strain 807-13, O149:NM:K88(STb+, LT+), was isolated from the feces of a neonatal diarrheic foal. E. coli 807-13 was examined for adhesion to brush border membranes (BBM) from foals, adult horses and pigs, and its pathogenicity was assessed in neonatal foals and pigs. E. coli 807-13 did not adhere to equine BBM but adhered to pig BBM. It did not cause diarrhea nor did it colonize the intestinal epithelium of 3 colostrum-deprived and 3 suckled foals challenged at 24 h of age. Acute ulcerative gastritis and acute suppurative gastritis were observed in 2 colostrum-deprived challenged foals, and acute neutrophilic enteritis was observed in 1 colostrum-deprived and in 1 suckled challenged foal. No similar histopathologic lesions were detected in the control foals. Both gnotobiotic and suckled pigs developed diarrhea after challenge exposure to E. coli 807-13 and the intestinal epithelium of the pigs was colonized. Histopathologic evidence of gastritis and enteritis among the foals indicated some complicity of E. coli 807-13 in foal enteric disease.

References

Nov 1, 1991·Equine Veterinary Journal·G F BrowningP D Rossdale
Sep 1, 1986·Veterinary Research Communications·L Ooms, A Degryse
Sep 1, 1986·Veterinary Microbiology·A C WardJ L Traub-Dargatz
Jun 1, 1982·Microbiological Reviews·W Gaastra, F K de Graaf
Oct 1, 1984·Veterinary Microbiology·S TziporiK L Ward
Feb 1, 1993·Veterinary Microbiology·D C HirshW D Wilson
Feb 1, 1996·Veterinary Microbiology·R E HollandR D Walker

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Citations

Aug 22, 2000·The Veterinary Quarterly·E van DuijkerenW Gaastra
Jan 6, 2015·Journal of Equine Science·Saori IshizakaHiroshi Matsuda
Dec 20, 2011·Veterinary Microbiology·F A UzalJ G Songer
Jun 7, 2015·The Veterinary Clinics of North America. Equine Practice·Francisco A Uzal, Santiago S Diab
Apr 20, 2011·Veterinary Pathology·S S DiabF A Uzal

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