Experimental inoculation of pregnant swine with type 1 bovine viral diarrhoea virus

Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health
P H WalzR K Maes

Abstract

The ability of bovine viral diarrhoea virus type 1 (BVDV-1) to induce transplacental infection in pigs was evaluated. Control pigs (n = 4) were sham-inoculated while infected pigs (n = 4) were intranasally inoculated with BVDV-1 on day 65 of gestation. Blood samples were tested throughout the study for BVDV and antibody to BVDV. On day 110 of gestation, a Caesarean section was performed. Serum was obtained for virus isolation and antibody determination from all piglets, and all experimental animals were killed. Tissues were collected for virus isolation and histopathology. Bovine viral diarrhoea virus was isolated on days 5 and 7 after infection and seroconversion was demonstrated in all infected gilts; however, BVDV was only isolated from one fetus from an infected pig. Viraemia and seroconversion were demonstrated in the pregnant gilts; however, transplacental infection at day 65 of gestation in the pig was not consistently demonstrated.

References

Aug 1, 1994·Journal of Comparative Pathology·D J Paton, S H Done
Jul 18, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·Z ZupancićV Staresina
Dec 18, 2002·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M Stokstad, T Løken
Dec 31, 2002·The Veterinary Record·D A GrahamS J McCullough

❮ Previous
Next ❯

Citations

Nov 4, 2009·Animal Health Research Reviews·Thomas Passler, Paul H Walz
Apr 9, 2014·Veterinary Research·Thomas PasslerPaul H Walz
May 23, 2012·Veterinary Microbiology·Yu DengGuang-Zhi Tong
Feb 2, 2010·The Veterinary Clinics of North America. Food Animal Practice·Julia F Ridpath
May 11, 2010·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Oscar CabezónJoaquim Segalés
Jun 4, 2020·Viruses·Luís Guilherme de OliveiraIgor R H Gatto

❮ Previous
Next ❯

Related Concepts

Related Feeds

CZI Human Cell Atlas Seed Network

The aim of the Human Cell Atlas (HCA) is to build reference maps of all human cells in order to enhance our understanding of health and disease. The Seed Networks for the HCA project aims to bring together collaborators with different areas of expertise in order to facilitate the development of the HCA. Find the latest research from members of the HCA Seed Networks here.