Experimental lens-induced granulomatous endophthalmitis in common laboratory animals

Ophthalmic Research
G E MarakA Sliwinski

Abstract

Guinea pigs and mice after immunization with lens proteins were observed to develop a typical form of experimental phacoanaphylactic endophthalmitis after lens injury. Sensitization to lens protein elicited a good antibody response in rabbits, however no disease developed after lens injury. This is another example of frequent discrepancies between autoimmune responses and autoimmune disease and indicates the importance of investigating mechanisms of phlogogenicity in autoimmune disease.

Citations

Oct 6, 2001·Progress in Retinal and Eye Research·M D de Smet, C C Chan
Mar 28, 2001·Ryōikibetsu shōkōgun shirīzu·S Nakamura, S Ohno
Nov 1, 1987·Survey of Ophthalmology·N A RaoG E Marak
Jul 1, 1994·The Veterinary Clinics of North America. Small Animal Practice·S Bistner
May 13, 2017·Veterinary Pathology·Cindy FarmanEvan A Thackaberry
Jun 9, 2001·Veterinary Ophthalmology·A. Van Der Woerdt

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