PMID: 19936465Nov 26, 2009Paper

Experimental myocardium infarction in rats: analysis of the model

Arquivos brasileiros de cardiologia
Leonardo A M ZornoffJoel Spadaro

Abstract

One of the most often used strategies to study the physiopathological alterations caused by coronary occlusion is the use of the experimental infarction model in rats. Among other factors, this is due to the similarities in the physiopathological alterations that occur after the infarction in humans. One must consider, however, that this model has characteristics that can hinder the use as well as the interpretation of eventual outcomes. Thus, this review aims at analyzing the main characteristics of the experimental infarction model in rats, discussing the coronary occlusion technique, the consequences and the methods of morphological and functional assessment of the infarction and its clinical implications.

Citations

Sep 8, 2017·Experimental Physiology·Alcione Lescano de Souza JuniorRui Curi
Sep 8, 2011·Journal of Cellular and Molecular Medicine·C G ManoleL M Popescu
May 28, 2011·Journal of Applied Physiology·Paula F MartinezMarina P Okoshi
Jul 6, 2014·Interactive Cardiovascular and Thoracic Surgery·Sven PeterssNawid Khaladj
Aug 26, 2017·Experimental Physiology·Vítor Scotta HentschkePedro Dal Lago
May 30, 2020·Journal of Cellular and Molecular Medicine·Bruna Letícia Buzati PereiraMarcos Ferreira Minicucci
Feb 23, 2013·Journal of Applied Physiology·José B N MoreiraPatricia C Brum
Jun 29, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Paula S AzevedoLeonardo A M Zornoff
Nov 9, 2017·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Colleen NofiEduard I Dedkov
Jan 10, 2019·Journal of Biomedical Science·Jonatas Rafael de OliveiraLuciane Dias de Oliveira
Mar 30, 2017·Journal of Medical Engineering & Technology·Nurhafizah MahriMohd Alauddin Mohd Ali
Nov 13, 2019·Journal of Neuroendocrinology·Ranjan K RoyDaryl O Schwenke
Jun 17, 2021·Arquivos brasileiros de cardiologia·Bruna C OliveiraSergio A R Paiva

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