Experimental pain sensitivity in women with temporomandibular disorders and pain-free controls: the relationship to orofacial muscular contraction and cardiovascular responses

The Clinical Journal of Pain
Christine MohnStein Knardahl

Abstract

Chronic pain may result both from a generalized hypersensitivity to acute pain, suggestive of central sensitization processes, and dysfunction of the endogenous pain regulatory system. One purpose of this study was to compare experimental pain sensitivity at several anatomic sites in temporomandibular disorder (TMD) patients and pain-free controls during baseline and after standardized mechanical load of the orofacial region. A second purpose was to compare the pain-modulating effects of cardiovascular responses in TMD patients and pain-free controls. Experimental pain was induced by electrocutaneous stimulation of the dorsal left hand and pressure algometry at the right masseter muscle and the sternum. The pain sensitivity of the orofacial region was manipulated by isometric contraction of the masseter muscles. Elevations of mean arterial pressure and heart rate were induced by a simulated job interview. At baseline, the TMD patients exhibited a significantly higher electrocutaneous pain threshold. Relative to the healthy controls, the TMD patients reported increased electrocutaneous and pressure pain sensitivity after isometric contraction of the orofacial region. In addition, there were correlations between mean arterial pre...Continue Reading

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Citations

Dec 17, 2009·Experimental Brain Research·César Fernández-de-las-PeñasPeter Svensson
Jul 14, 2009·The Journal of Pain : Official Journal of the American Pain Society·César Fernández-de-las-PeñasPeter Svensson
May 5, 2009·The Journal of Pain : Official Journal of the American Pain Society·Kathleen C LightWilliam Maixner
Dec 15, 2012·European Journal of Pain : EJP·K F KoltynA G Brellenthin
Mar 19, 2014·The Journal of Pain : Official Journal of the American Pain Society·Matthew T Knauf, Kelli F Koltyn
Apr 18, 2015·BioMed Research International·Włodzimierz WięckiewiczMariusz Lipski
May 31, 2017·Pain Practice : the Official Journal of World Institute of Pain·Roy La ToucheDaniel Muñoz-García
Aug 15, 2012·Critical Care Medicine·Sea Mi ParkAxel J Rosengart
Jun 17, 2020·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Maryam JessriStephan Schug
Sep 15, 2017·Journal of Oral Science·Jorge ChaurandJulio López-Valdés
Jun 20, 2018·Scandinavian Journal of Pain·Christine MohnStein Knardahl
Nov 21, 2020·Journal of Clinical Medicine·César Fernández-de-Las-Peñas, Harry Von Piekartz

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