Experimental papilledema produced by cyclocryotherapy

American Journal of Ophthalmology
D S Minckler, M O Tso

Abstract

Cyclocryotherapy was a reliable method of producing prolonged decreased intraocular pressure and papilledema in the rhesus monkey. Histologic changes in papilledema caused by decreased pressure were indistinguishable from those in papilledema from increased intracranial pressure. Electron microscopic observations in papilledema after cyclocryotherapy suggested that the principal morphologic alteration in the optic disk is axonal swelling. Additionally, many mitochondria accumulated in some swollen axons. These changes, observed at the ultrastructural level, suggest that alternations of axoplasmic transport may play a significant role in the pathogenesis of swelling of the disk.

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Citations

Oct 11, 2015·Progress in Retinal and Eye Research·Sohan Singh Hayreh
Sep 1, 1983·Survey of Ophthalmology·M Prost
Jan 1, 1983·Experimental Eye Research·B B Floyd, D S Minckler
May 1, 1978·American Journal of Ophthalmology·A R Bellows, W M Grant
Mar 1, 1981·The British Journal of Ophthalmology·D TaylorM Dillon
Nov 1, 1981·The British Journal of Ophthalmology·R L Radius, D R Anderson
Sep 19, 2019·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Stefano VeraldiCarlo Gelmetti
Mar 27, 2021·Taiwan Journal of Ophthalmology·Benson S ChenValérie Biousse
Jan 1, 1977·Experimental Eye Research·D G Cogan, T Kuwabara

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