Experimental perfusions through the anterior and vitreous chambers with possible relationships to malignant glaucoma

American Journal of Ophthalmology
David L EpsteinW M Grant

Abstract

Enucleated eyes were perfused alternately via the anterior and vitreous chambers. At low intraocular pressure (IOP), vitreous humor presented considerable resistance to forward flow of perfusion fluid in calf eyes, but not in human eyes. In human eyes when the perfusion pressure was increased to 60 mm Hg, the resistance to flow forward from the vitreous body increased, but became practically nil again when the IOP was decreased. At high pressure the volume of the vitreous body apparently increases and the anterior hyaloid membrane probably presses against the ciliary body, reducing the area of hyaloid membrane through which fluid can flow. Whether increased perfusion pressure can in some other manner change the permeability of human vitreous to resemble that of the calf remains unanswered. Our results suggest that factors other than, or in addition to, simple diversion of aqeous humor must be important in malignant glaucoma.

References

Mar 1, 1978·Ophthalmology·R N Shaffer, H D Hoskins
Jul 1, 1978·American Journal of Ophthalmology·D L EpsteinW M Grant
Mar 1, 1973·American Journal of Ophthalmology·M A Johnstone, W G Grant
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Sep 1, 1962·Archives of Ophthalmology·P A CHANDLER, W M GRANT

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Citations

Aug 15, 1984·American Journal of Ophthalmology·D L EpsteinC A Puliafito
Feb 15, 1987·American Journal of Ophthalmology·D L Epstein
May 3, 2002·Ophthalmology·James C TsaiRoger A Hitchings
Jan 1, 1992·Documenta Ophthalmologica. Advances in Ophthalmology·J P Ellant, S A Obstbaum
Jan 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A Aminlari, J W Sassani
Sep 1, 1993·Ophthalmology·C TelloR Ritch
Aug 23, 2011·Medical Hypotheses·Rosana GeromettaOscar A Candia
Jan 3, 2013·Clinical & Experimental Ophthalmology·Tiago S PrataRobert Ritch
May 18, 2011·Clinical & Experimental Ophthalmology·Weng T Ng, William Morgan
Feb 3, 2015·Survey of Ophthalmology·Kevin KaplowitzJames C Tsai
Feb 5, 2013·Ophthalmology·Paaraj DaveChandra S Garudadri
Dec 1, 1994·Seminars in Ophthalmology·M M Zaltas, J S Schuman
Apr 26, 2008·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Zvia Burgansky-EliashJoel S Schuman
Jul 26, 2002·Journal of Glaucoma·Brian A FrancisDon S Minckler
Jan 11, 2002·Journal of Biomechanical Engineering·J J HeysM J Taravella
Mar 2, 2013·Eye·A Koukkoulli, R Rahman
Aug 1, 1991·The British Journal of Ophthalmology·S MelamedM Blumenthal
Nov 11, 2005·Journal of the American Veterinary Medical Association·Jessica M C CzederpiltzPaul E Miller
May 30, 2019·European Journal of Ophthalmology·Natasha Gautam SethSurinder Singh Pandav
May 29, 2007·Journal of Cataract and Refractive Surgery
Aug 31, 2019·European Journal of Ophthalmology·Shriji Patel
Mar 2, 2019·Journal of Glaucoma·Jason A GreenfieldDavid S Greenfield
Jul 16, 1999·Ophthalmology·E C Massicotte, J S Schuman
Jan 1, 1984·Experimental Eye Research·B Y YueM O Tso

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