PMID: 2424696Jan 1, 1986

Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes

Diabetes/metabolism Reviews
G C WeirS Bonner-Weir

Abstract

No abstract listed.

References

Insulin release: the fuel hypothesis

Apr 1, 1979·Metabolism: Clinical and Experimental·W J MalaisseJ C Hutton

The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man

Apr 1, 1976·The New England Journal of Medicine·C R KahnJ Roth

Immediate and time-dependent effects of glucose on insulin release from rat pancreatic tissue. Evidence for different mechanisms of action

Apr 1, 1978·The Journal of Clinical Investigation·V GrillE Cerasi

Circulating proinsulin in patients with maturity onset diabetes

Dec 1, 1977·The American Journal of Medicine·M E MakoA H Rubenstein

The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

Nov 1, 1978·Diabetologia·P Westermark, E Wilander

Development of polyploidy in B-cells of normal and diabetic mice

Feb 1, 1979·Acta Endocrinologica·M N Pohl, F J Swartz

Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings

Nov 8, 1979·The New England Journal of Medicine·D A LangR C Turner

Differential volumetry of A, B and D cells in the pancreatic islets of diabetic and nondiabetic subjects

Nov 1, 1979·The Tohoku Journal of Experimental Medicine·K SaitoT Takahashi

Chemical diabetes in the adult rat as the spontaneous evolution of neonatal diabetes

Dec 1, 1979·Diabetologia·B PorthaG Rosselin

Maintenance of basal plasma glucose and insulin concentrations in maturity-onset diabetes

Mar 1, 1979·Diabetes·R R Holman, R C Turner

Potentiation of insulin secretory responses by plasma glucose levels in man: evidence that hyperglycemia in diabetes compensates for imparied glucose potentiation

Jun 1, 1979·The Journal of Clinical Endocrinology and Metabolism·J B HalterD Porte

Polyploidy in the pancreas of the normal and diabetic mutant mouse

May 1, 1976·Diabetologia·M G Ehrie, F J Swartz

Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjects

Sep 1, 1976·The Journal of Clinical Investigation·J P PalmerJ W Ensinck

Nonketotic diabetes mellitus: insulin deficiency or insulin resistance?

Jan 1, 1976·The American Journal of Medicine·G ReavenJ M Olefsky

Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity

Jul 1, 1977·Diabetes·J M Olefsky, G Reaven

Insulin responses in equivocal and definite diabetes, with special reference to subjects who had mild glucose intolerance but later developed definite diabetes

Oct 1, 1977·Diabetes·K KosakaT Kuzuya

An effect of hyposmolarity on insulin release in vitro

Mar 1, 1975·The American Journal of Physiology·W G BlackardA E Renold

Beta-cell function improved by supplementing basal insulin secretion in mild diabetes

May 22, 1976·British Medical Journal·R C TurnerE Harris

Abnormal insulin secretion in a streptozocin model of diabetes. Effects of insulin treatment

Jul 1, 1985·Diabetes·J L LeahyG C Weir

Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas

Feb 1, 1985·The Journal of Clinical Investigation·A HisatomiR H Unger

Unresponsiveness to glucose in a streptozocin model of diabetes. Inappropriate insulin and glucagon responses to a reduction of glucose concentration

Jul 1, 1985·Diabetes·J L Leahy, G C Weir

Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions

Mar 1, 1986·The Journal of Clinical Investigation·J L LeahyG C Weir

Acanthosis nigricans in obese women with hyperandrogenism. Characterization of an insulin-resistant state distinct from the type A and B syndromes

Feb 1, 1985·Diabetes·J S FlierJ W Rowe

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus

Mar 1, 1985·Diabetes·W T GarveyO G Kolterman

Impaired insulin biosynthetic capacity in a rat model for non-insulin-dependent diabetes. Studies with dexamethasone

Mar 1, 1985·Diabetes·S GiddingsM A Permutt

Modulation of proinsulin messenger RNA after partial pancreatectomy in rats. Relationships to glucose homeostasis

Jun 1, 1985·The Journal of Clinical Investigation·M J OrlandM A Permutt

Decreased glucose-induced insulin release and biosynthesis by islets of rats with non-insulin-dependent diabetes: effect of tissue culture

Nov 1, 1985·Endocrinology·B Portha

Diabetogenic action of streptozotocin: relationship of dose to metabolic response

Nov 1, 1969·The Journal of Clinical Investigation·A JunodA E Renold

Diabetogenic effect of streptozotocin in the rat during the perinatal period

Nov 1, 1974·Diabetes·B PorthaG Rosselin

Characterization of the effects of arginine and glucose on glucagon and insulin release from the perfused rat pancreas

Oct 1, 1974·The Journal of Clinical Investigation·J E GerichG M Grodsky

Acute and steady-state insulin responses to glucose in nonobese diabetic subjects

Jul 1, 1972·The Journal of Clinical Investigation·R L Lerner, D Porte

The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus

Jun 1, 1967·Acta Endocrinologica·E Cerasi, R Luft

A rat pancreas-small gut preparation for the study of intestinal factor(s) and insulin release

Nov 1, 1969·Diabetes·J C PenhosF W Wolff

Studies of the metabolism of isolated livers of normal and alloxan-diabetic rats perfused with insulin

May 1, 1968·Diabetes·D E Haft

Study of the relationship between glucose and insulin responses to an oral glucose load in man

Sep 1, 1968·Diabetes·G Reaven, R Miller

Control of insulin secretion during fasting hyperglycemia in adult diabetics and in nondiabetic subjects during infusion of glucose

Oct 1, 1969·The Journal of Clinical Investigation·C J GoodnerJ H Werbach

Plasma insulin responses to glucose and tolbutamide of normal weight and obese diabetic and nondiabetic subjects

Dec 1, 1966·Diabetes·M Perley, D M Kipnis

Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus

Mar 1, 1967·The Journal of Clinical Investigation·H S SeltzerM T Brennan

Pathophysiology of insulin secretion in non-insulin-dependent diabetes mellitus

Sep 1, 1984·Diabetes Care·W K WardD Porte

Responses of neonatal rat islets to streptozotocin: limited B-cell regeneration and hyperglycemia

Jan 1, 1981·Diabetes·S Bonner-WeirG C Weir

Histogenesis of the endocrine pancreas in newborn rats after destruction by streptozotocin. An immunocytochemical study

Jan 1, 1981·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·D CantenysL Picon

Islet secretion in a new experimental model for non-insulin-dependent diabetes

Jul 1, 1981·Diabetes·G C WeirS Bonner-Weir

Limited B cell regeneration in a B cell deficient rat model: studies with dexamethasone

Sep 1, 1981·Metabolism: Clinical and Experimental·S Bonner-WeirG C Weir

Regulation of insulin release by calcium

Oct 1, 1981·Physiological Reviews·C B Wollheim, G W Sharp

Ultrastructural study of pancreatic B cell regeneration in newborn rats after destruction by streptozotocin

Jan 1, 1982·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·M C DutrillauxE Hollande

Quantitation of endocrine cell content in the pancreas of nondiabetic and diabetic humans

Aug 1, 1982·Diabetes·Y StefanR H Unger

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release

Jun 1, 1983·The Journal of Clinical Investigation·S Bonner-WeirG C Weir

Pancreatic and gut hormones during fasting: insulin, glucagon, and somatostatin

Jan 1, 1984·Hormone Research·D F TrentG C Weir

Abnormal glucose regulation of insulin secretion in models of reduced B-cell mass

Jul 1, 1984·Diabetes·J L LeahyG C Weir

An in vivo analysis of pancreatic protein and insulin biosynthesis in a rat model for non-insulin-dependent diabetes

May 1, 1984·The Journal of Clinical Investigation·M A PermuttS Giddings

Glucoreceptor mechanisms and the control of insulin release and biosynthesis

Jan 1, 1980·Diabetologia·S J Ashcroft

Mechanism of glucose-induced insulin secretion

Apr 1, 1980·Physiological Reviews·C J Hedeskov

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets

Nov 19, 1981·Nature·H YamamotoH Okamoto

Immunotherapy of type I diabetes

Sep 1, 1983·Diabetes Care·G S Eisenbarth

Elevated proinsulin biosynthesis in vitro from a rat model of non-insulin-dependent diabetes mellitus

Mar 1, 1983·Diabetes·P A HalbanG C Weir

Three mutant insulins in man

Apr 7, 1983·Nature·S ShoelsonH S Tager

Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas

May 1, 1983·Diabetes·M H GiroixL Picon

Glucose- and arginine-induced insulin and glucagon responses from the isolated perfused pancreas of the BB-Wistar diabetic rat. Evidence for selective impairment of glucose regulation

Apr 1, 1983·Acta Endocrinologica·V Grill, L Herberg

Does day-long absolute hypoinsulinemia characterize the patient with non-insulin-dependent diabetes mellitus?

Aug 1, 1983·Metabolism: Clinical and Experimental·G LiuG Reaven

Cellular composition of the human diabetic pancreas

May 1, 1983·Diabetologia·J RahierJ C Henquin

Type I diabetes mellitus in monozygotic twins: chronic progressive beta cell dysfunction

Sep 1, 1983·Annals of Internal Medicine·S SrikantaG S Eisenbarth

Abnormal islet and adipocyte function in young B-cell-deficient rats with near-normoglycemia

Feb 1, 1984·Diabetes·D F TrentG C Weir

Effects of cyclosporine immunosuppression in insulin-dependent diabetes mellitus of recent onset

Mar 30, 1984·Science·C R StillerB M Wolfe

Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus

Jun 1, 1984·Diabetes·O P GandaG S Eisenbarth

Insulin therapy in obese, non-insulin-dependent diabetes induces improvements in insulin action and secretion that are maintained for two weeks after insulin withdrawal

Jul 1, 1984·Diabetes·W J AndrewsG Reaven

Lilly lecture 1983. Abnormal products of the human insulin gene

Jul 1, 1984·Diabetes·H S Tager

Insulin gene structure and function: a review of studies using recombinant DNA methodology

Jul 1, 1984·Diabetes Care·M A PermuttS Giddings

Impaired insulin action in rats with non-insulin-dependent diabetes

Sep 1, 1984·Diabetes·J LevyL V Avioli

Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects

Oct 1, 1984·The Journal of Clinical Investigation·C BogardusD M Mott

Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus

Oct 1, 1984·The Journal of Clinical Investigation·W K WardD Porte

Hormonal and non-hormonal protein biosynthesis in the pancreatic beta cell of the intact rat after prolonged hyperglycaemia

Nov 1, 1984·Acta Endocrinologica·J Logothetopoulos, N Valiquette

Insulin within islets is a physiologic glucagon release inhibitor

Dec 1, 1984·The Journal of Clinical Investigation·H MaruyamaR H Unger

Effect of genetic background on the capacity for islet cell replication in mice

Oct 1, 1984·Diabetologia·I Swenne, A Andersson

Subtotal pancreatectomy in five different rat strains: incidence and course of development of diabetes

Jul 1, 1984·Diabetologia·F Kaufmann, R R Rodriguez

Non-insulin-dependent diabetes mellitus: interplay between B-cell inadequacy and insulin resistance

Oct 1, 1982·The American Journal of Medicine·G C Weir

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus

Oct 1, 1982·Diabetologia·R A DeFronzoE Ferrannini

Insulin treatment reverses the insulin resistance of type II diabetes mellitus

Jul 1, 1982·Diabetes Care·J A ScarlettO G Kolterman

Glucose modulation of insulin and glucagon secretion in nondiabetic and diabetic man

Jun 1, 1982·Diabetes·P M HollanderJ P Palmer

The role of glucose in the in vitro regulation of cell cycle kinetics and proliferation of fetal pancreatic B-cells

Sep 1, 1982·Diabetes·I Swenne

Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment

Jan 1, 1980·Diabetologia·K KosakaR Hagura

Insulin secretion in maturity-onset-diabetes. Function of isolated islets

Aug 1, 1980·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·D LohmannH Mättig

Familial insulin resistance with acanthosis nigricans, acral hypertrophy, and muscle cramps

Oct 23, 1980·The New England Journal of Medicine·J S FlierL Landsberg

The pancreatic islets in diabetes

Jan 1, 1981·The American Journal of Medicine·W Gepts, P M Lecompte

Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes

Jan 1, 1981·The American Journal of Medicine·J M Olefsky, O G Kolterman

Polyploidy in islets of normal and diabetic humans

Feb 1, 1981·Human Pathology·M N PohlP H Carstens

Blood-brain glucose transfer: repression in chronic hyperglycemia

Oct 23, 1981·Science·A Gjedde, C Crone

Improvement of insulin secretion but not insulin resistance after short term control of plasma glucose in obese type II diabetics

Feb 1, 1982·The Journal of Clinical Endocrinology and Metabolism·H HidakaR H Unger

The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia

Feb 1, 1982·Metabolism: Clinical and Experimental·P Vague, J P Moulin

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

Oct 1, 1981·The Journal of Clinical Investigation·O G KoltermanJ M Olefsky

Quantitative estimation of the pancreatic islet tissue in diabetic subjects

Sep 1, 1955·Diabetes·N MACLEAN, R F OGILVIE

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

Apr 13, 1963·Lancet·P J RANDLEE A NEWSHOLME

Excessive insulin response to glucose in obese subjects as measured by immunochemical assay

May 1, 1963·Diabetes·J H KARAMP H FORSHAM

Extractable insulin of pancreas; correlation with pathological and clinical findings in diabetic and nondiabetic cases

Mar 1, 1952·Diabetes·G A WRENSHALLR C RITCHIE

Control of moulting in an insect

Nov 7, 1970·Nature·S B Weir

Citations

Genetic epidemiology of non-insulin-dependent diabetes

Dec 1, 1994·Diabetes/metabolism Reviews·P Valsania, P Micossi

The regulation of pancreatic islet blood flow

Dec 1, 1994·Diabetes/metabolism Reviews·L Jansson

Desensitization of the insulin-secreting beta cell

Jan 1, 1992·Journal of Cellular Biochemistry·G M Grodsky, J L Bolaffi

Growth hormone regulation of DNA replication, but not insulin production, is partly mediated by somatomedin-C/insulin-like growth factor I in isolated pancreatic islets from adult rats

Mar 1, 1989·Diabetologia·I Swenne, D J Hill

Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat

Jan 1, 1993·Diabetologia·C G OstensonS Efendic

Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis

Jul 1, 1992·Diabetologia·C N Hales, D J Barker

No glucotoxicity after 53 hours of 6.0 mmol/l hyperglycaemia in normal man

Aug 1, 1991·Diabetologia·H FlaxR C Turner

Pancreatic beta-cell growth and diabetes mellitus

Mar 1, 1992·Diabetologia·I Swenne

The role of islet secretory function in the development of diabetes in the GK Wistar rat

Sep 1, 1994·Diabetologia·S J HughesY Goto

Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level

Sep 1, 1991·Diabetologia·J L Leahy, G C Weir

Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice

Jun 1, 1991·Diabetologia·O KorsgrenA Andersson

Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period

May 1, 1996·Diabetologia·R N WangG Klöppel

Prolonged exposure of pancreatic islets isolated from "pre-diabetic" non-obese diabetic mice to a high glucose concentration does not impair beta-cell function

Jan 1, 1991·Diabetologia·D L EizirikS Sandler

Irreversible loss of normal beta-cell regulation by glucose in neonatally streptozotocin diabetic rats

Apr 1, 1994·Diabetologia·K InoueV Grill

Beta-cell proliferation in normal and streptozotocin-treated newborn rats: site, dynamics and capacity

Nov 1, 1994·Diabetologia·R N WangG Klöppel

Cardiomyopathy associated with noninsulin-dependent diabetes

Sep 18, 1991·Molecular and Cellular Biochemistry·S W Schaffer

Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas

Nov 27, 2004·Diabetologia·Marianne O LarsenJ J Holst

Enhancement by streptozotocin-induced diabetes of pancreatic prolyl endopeptidase activity in neonatal rats

Feb 24, 1994·Regulatory Peptides·P Salers

Adaptive response in beta-cell function in pancreatic islets isolated from partially pancreatectomized rats

Aug 1, 1992·Molecular and Cellular Endocrinology·S SandlerN Welsh

Effects of bezafibrate on beta-cell function of rat pancreatic islets

Aug 31, 2001·European Journal of Pharmacology·H YoshikawaHajime Nawata

The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose

Feb 5, 1999·European Journal of Pharmacology·R LupiP Marchetti

Insulin secretion and biosynthesis by the perfused pancreas of spontaneously hypertensive rats

Jan 27, 1999·Metabolism: Clinical and Experimental·K TanigawaK Tamura

Purified murine islet allografts: islet engraftment as influenced by implantation site and glucotoxicity

Apr 9, 1998·Transplantation Proceedings·I M MahmoudM A Ghoneim

Transplantation of feline islets of Langerhans in the subretinal space of cat eyes

Apr 9, 1998·Transplantation Proceedings·D L HatchellC A Toth

Sequential changes in serum insulin concentration during development of non-insulin-dependent diabetes

Jun 17, 1989·Lancet·M F SaadP H Bennett

Evaluation of the site(s) of glycation in human proinsulin by ion-trap LCQ electrospray ionization mass spectrometry

Apr 11, 2003·Regulatory Peptides·Aine M McKillopFinbarr P M O'Harte

Pathogenesis of NIDDM--a disease of deficient insulin secretion

May 1, 1988·Baillière's Clinical Endocrinology and Metabolism·R C TurnerJ Levy

The role of cyclic AMP in the pathogenesis of glucose desensitization in rat pancreatic islets

May 10, 2001·Pancreas·H YoshikawaHajime Nawata

Glucosamine-induced beta-cell dysfunction: a possible involvement of glucokinase or glucose-transporter type 2

Mar 15, 2002·Pancreas·Hiroyasu YoshikawaHajime Nawata

Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine A, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days

May 26, 2001·Transplantation·L WennbergO Korsgren

Functional beta-cell mass and insulin sensitivity is decreased in insulin-independent pancreas-kidney recipients

Feb 10, 2009·Transplantation·Pieter GillardChantal Mathieu

Cell therapy for type 2 diabetes: is it desirable and can we get it?

Oct 18, 2008·Diabetes, Obesity & Metabolism·P A Halban

Comparison of indices of islet B-cell function in type 2 diabetes in relation to insulin effectiveness and clinical outcome

Aug 1, 1991·Diabetic Medicine : a Journal of the British Diabetic Association·S W CoppackT D Hockaday

β-cell mass in people with type 2 diabetes

Jan 24, 2011·Journal of Diabetes Investigation·Jae-Hyoung ChoKun-Ho Yoon

Minimal chronic hyperglycemia is a critical determinant of impaired insulin secretion after an incomplete pancreatectomy

May 1, 1988·The Journal of Clinical Investigation·J L LeahyG C Weir

Islets of Langerhans: the puzzle of intraislet interactions and their relevance to diabetes

Apr 1, 1990·The Journal of Clinical Investigation·G C Weir, S Bonner-Weir

Reversal of beta-cell suppression in vitro in pancreatic islets isolated from nonobese diabetic mice during the phase preceding insulin-dependent diabetes mellitus

Jun 1, 1990·The Journal of Clinical Investigation·E StrandellS Sandler

Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background

Dec 1, 1990·The Journal of Clinical Investigation·O KorsgrenA Andersson

The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environment

Jul 1, 1992·The Journal of Clinical Investigation·B ThorensG C Weir

Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function

Oct 1, 1992·The Journal of Clinical Investigation·D L EizirikC Hellerström

Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice

Aug 1, 1995·The Journal of Clinical Investigation·L JanssonA Andersson

A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes

Jul 11, 2009·Journal of Clinical Biochemistry and Nutrition·Tsui-Wei ChouMing-Hoang Lai

Development of an alternative non-obese non-genetic rat model of type 2 diabetes using caffeine and streptozotocin

Jun 21, 2014·Pharmacological Reports : PR·Pragalathan Naidoo, Md Shahidul Islam

New perspectives on the structure and function of the normal and diabetic beta-cell

Jan 1, 1991·Upsala Journal of Medical Sciences·C HellerströmA Andersson

Pentamidine-induced beta cell toxicity is not preventable by high glucose

Aug 1, 1989·The American Journal of the Medical Sciences·D B Zhou, E Ipp

The role of ABO blood groups in infections induced by Staphylococcus saprophyticus and Pseudomonas aeruginosa

Oct 1, 1995·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·J GeiselJ Beuth

Cellular glucose availability and glucagon-like peptide-1

Sep 13, 2011·Progress in Biophysics and Molecular Biology·Jae-Hyung ParkDae-Kyu Song

Cytokine production by islets in health and diabetes: cellular origin, regulation and function

Jan 26, 2010·Trends in Endocrinology and Metabolism : TEM·Marc Y DonathJan A Ehses

Beta-cell apoptosis in type 2 diabetes: quantitative and functional consequences

Jul 22, 2008·Diabetes & Metabolism·R Lupi, S Del Prato

Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells

Aug 31, 2004·Journal of Thrombosis and Haemostasis : JTH·D E FerraraS S Pierangeli

Evaluation of beta-cell mass and function in the Göttingen minipig

Oct 9, 2007·Diabetes, Obesity & Metabolism·Marianne O LarsenT Bock

Reversal of experimental diabetes by multiple bone marrow transplantation

Jan 27, 2005·Biochemical and Biophysical Research Communications·Meenal BanerjeeRamesh R Bhonde

Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice

Jan 1, 1997·Metabolism: Clinical and Experimental·B AhrénF Sundler

Immunoprotection in spontaneous remission of type 1 diabetes: long-term follow-up results

Feb 1, 1993·Diabetes Research and Clinical Practice·M T YilmazF Sipahioğlu

The relationship of diabetes, loss of glucose-induced insulin secretion, and GLUT2

Apr 1, 1993·Journal of Diabetes and Its Complications·G C Weir

Function and metabolism of pancreatic beta-cells maintained in culture following experimentally induced damage

Sep 1, 1989·Pharmacology & Toxicology·D L Eizirik, S Sandler

Animal models of type 2 diabetes with reduced pancreatic beta-cell mass

Oct 29, 2005·The International Journal of Biochemistry & Cell Biology·Pellegrino Masiello

Role of lymph-borne cells in the early stages of scrapie agent dissemination from the skin

Sep 20, 2005·Veterinary Immunology and Immunopathology·Anton GossnerJohn Hopkins

Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets

Jun 29, 2004·Diabetes·Kathrin MaedlerMarc Y Donath

Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy

Jul 29, 2006·Diabetes·Aleksey V MatveyenkoPeter C Butler

An in vivo investigation on the wound-healing effect of two medicinal herbs using an animal model with foot ulcer

Apr 3, 2008·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·T W LauP C Leung

The remission concept in type 1 diabetes and its significance in immune intervention

Dec 1, 1993·Diabetes/metabolism Reviews·M T Yilmaz

Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications

Feb 10, 2004·Diabetologia·Marc Y Donath, P A Halban

Identification of miR-9 as a negative factor of insulin secretion from beta cells

Feb 23, 2018·Journal of Physiology and Biochemistry·Dongzhi HuDalu Kong

Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number

Aug 15, 2003·Oncogene·Javier MartínMariano Barbacid

Immunohistological localization of the neural adhesion molecules L1 and N-CAM in the developing hippocampus of the mouse

Dec 1, 1990·Journal of Neurocytology·E Persohn, M Schachner

Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo

Nov 10, 2005·American Journal of Physiology. Endocrinology and Metabolism·Marianne O LarsenCarsten F Gotfredsen

Wall effects in sucrose density gradient centrifugation of viruses

Jan 1, 1989·Archives of Virology·A Boeyé, A De Rees

Quantitative trait loci mapping of phenotypic plasticity and genotype-environment interactions in plant and insect performance

Mar 30, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·C Tétard-JonesR F Preziosi

Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. 1992

Oct 26, 2013·International Journal of Epidemiology·C N Hales, D J P Barker

Successful pregnancy in a case of bladder and ovary endometriosis following cystoscopy-assisted laparoscopic resection

Jun 4, 2014·The Journal of Obstetrics and Gynaecology Research·Fumihisa ChishimaTatsuo Yamamoto

beta-cell failure in diabetes and preservation by clinical treatment

Mar 14, 2007·Endocrine Reviews·Bernardo L Wajchenberg

Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I

Oct 13, 2009·Endocrinology·Marianne Böni-SchnetzlerMarc Y Donath

Genetic factors of importance for beta-cell proliferation

Apr 1, 1993·Diabetes/metabolism Reviews·M WelshT Karlsson

Streptozotocin-Induced Diabetes Mellitus in Neonatal Rats: An insight into its applications to Induce Diabetic Complications

Apr 12, 2019·Current Diabetes Reviews·A B Mirza, S S Panchal

The effect of dexamethasone on B cell mass and function in partial pancreatctomized rats

Jan 1, 1988·The Korean Journal of Internal Medicine·H C Lee, K B Huh

Increase in B-cells in the pancreatic remnant after partial pancreatectomy in pigs. An immunocytochemical and functional study

Jan 1, 1989·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·M LöhrG Klöppel

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