Experimental study of a newly developed bilayer artificial skin

Biomaterials
S SuzukiY Ikada

Abstract

A bilayer artificial skin composed of an outer layer of silicone polymer and an inner sponge layer of collagen containing chondroitin 6-sulphate was developed by modifying the technique proposed by Yannas et al. The artificial skin was placed on the skin defects on the backs of rats. Histological observation indicated that fibroblasts and capillaries infiltrated into the pores and filled in lattice spaces, resulting in synthesis of the connective tissue matrix and absorption of the original network of collagen and chondroitin 6-sulphate. Epidermal cells migrated from the edge of the wound between the two layers. Post-operative contracture in the wound with the artificial skin was significantly less than in the control.

References

Apr 1, 1975·British Journal of Plastic Surgery·J H James, A C Watson
Apr 1, 1973·British Journal of Plastic Surgery·W H ChangL M Edelstein
Oct 1, 1973·Plastic and Reconstructive Surgery·R A Elliott, J G Hoehn
Jan 1, 1971·Scandinavian Journal of Plastic and Reconstructive Surgery·L O Lamke, S O Liljedahl
Jan 1, 1980·Journal of Biomedical Materials Research·I V Yannas, J F Burke
Mar 1, 1980·Journal of Biomedical Materials Research·I V YannasR H Rubenstein
Jul 1, 1980·Journal of Biomedical Materials Research·N DagalakisI V Yannas

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Citations

Aug 28, 2001·Journal of Biomedical Materials Research·K KawaiY Nishimura
Feb 1, 1991·British Journal of Plastic Surgery·K MatsudaY Ikada
Jun 1, 1995·British Journal of Plastic Surgery·S SuzukiY Ikada
Oct 1, 1993·Biomaterials·K MatsudaY Ikada
May 5, 2001·Biomaterials·K UlubayramN Hasirci
Jan 1, 1996·Tissue Engineering·S SuzukiK Morota
Jun 27, 2008·Tissue Engineering. Part a·Satoru TakemotoShigehiko Suzuki
Feb 16, 2010·The Journal of Trauma·Nele BrusselaersStan Monstrey
Jun 1, 1997·The British Journal of Dermatology·F Berthod, O Damour
May 21, 2009·Journal of Biomaterials Science. Polymer Edition·Yasuhiro MatsumotoYoshimitsu Kuroyanagi
Jan 1, 1995·Journal of Biomaterials Science. Polymer Edition·K MatsudaY Ikada
Nov 2, 2013·Journal of Materials Science. Materials in Medicine·Bouke K H L BoekemaMagda M W Ulrich
Jan 5, 2002·Annals of Plastic Surgery·N MorimotoY Nishimura
Nov 6, 2012·The Journal of Surgical Research·Pham Hieu LiemShigehiko Suzuki
Jan 26, 2011·Biotechnology Advances·R JayakumarH Tamura
Nov 10, 2009·Burns : Journal of the International Society for Burn Injuries·Vincent C van der VeenEsther Middelkoop
Jan 30, 2008·Burns : Journal of the International Society for Burn Injuries·Shuangyun LuHai Ying Gu
Sep 11, 2007·The Journal of Surgical Research·Naoki MorimotoTsuguyoshi Taira
Feb 6, 2007·Clinics in Dermatology·Jisun Cha, Vincent Falanga
Jul 21, 2005·The British Journal of Dermatology·H NakagawaK Akino
Oct 4, 2011·The Journal of Surgical Research·Artem AyvazyanShigehiko Suzuki
Jul 26, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Masaki NambuTomoharu Kiyosawa
Oct 22, 2015·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Chenyu HuangHiroshi Mizuno
Apr 20, 2005·The Journal of Surgical Research·Naoki MorimotoShigehiko Suzuki
Jun 30, 2015·Journal of Tissue Engineering and Regenerative Medicine·Nao HiwatashiShigehiko Suzuki
Apr 14, 2016·Tissue Engineering. Part a·Mathew N NicholasSaeid Amini-Nik
Oct 8, 2005·The Journal of Veterinary Medical Science·Akane TanakaHiroshi Matsuda
Apr 16, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Shigehiko SuzukiKatsuya Kawai
May 25, 2016·BioMed Research International·Chizuru JinnoShigehiko Suzuki
May 8, 2016·Cellular and Molecular Life Sciences : CMLS·Mathew N NicholasSaeid Amini-Nik
Oct 27, 2015·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Hiromu MasuokaShigehiko Suzuki
Aug 7, 2004·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Claudia Valenta, Barbara G Auner

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