PMID: 2123973Nov 1, 1990Paper

Experimental study of the course of the immune response at the urinary level following repeated oral vaccination

Minerva medica
F Negretti, P Casetta

Abstract

The Progression of the specific immunoreactions in the urines of rabbits vaccinated by oral route from 1 to 10 times with 20-40 billion of some antigens (E. coli, Proteus vulgaris, Staph aureus, Str. faecalis), administered daily or by-weekly, has been evaluated by agglutination and ELISA. The immunoenzymatic ELISA technique has revealed increases of specific immunoglobulins also one day after the first oral administration of the antigens and a final progression of IgA titres (after ten treatments) from 81% to 798%, according to the various antigens and the different posology. The highest values have been obtained using the posology of 40 billion and the bi-weekly sequence.

Related Concepts

Related Feeds

Antibodies: Agglutination

Antibody-mediated agglutination is the clumping of cells in the presence of antibody, which binds multiple cells together. This enhances the clearance of pathogens. Find the latest research on antibody-mediated agglutination here.