PMID: 8962525Oct 1, 1996Paper

Experimental study of ureteral free grafts. III. Histological findings

Archivos españoles de urología
F J Blasco CasaresA Gelabert Mas

Abstract

To analyze histological findings in rat ureter used as free autologous graft and compare them with two controls. They were randomly distributed into four groups: NU group (n = 20), ureter from healthy rats; SC group (n = 15), ureter from rats undergoing ureterolysis, the surgical control group; AU group (n = 13), rats with ureter used as ANIFG (autologous non-integrated free graft); RU group (n = 14), rats with ureter used as AIFG (autologous integrated free graft). For the histological study, ureteral cross sections were obtained (A proximal, B middle, and C distal) and kidney (K) was studied. In addition, in the RU group, we obtained one cross section above the proximal suture (D), one below the distal suture (E), and two longitudinal sections of the surgical anastomoses (F and G). The results showed a histological similarity between the NU, SC and AU groups and an apparent viability of all RU group ureters in which necrosis has not been found. SC group: Mild edema could be noted in the lamina propria in some of the sections. None of the three ureteral layers showed any fibrosis or other lesions. AU group: All layers were preserved. The urothelium showed changes from mild hyperplasia to a wider area of denudation. Some of the...Continue Reading

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