PMID: 6108723Jan 1, 1980Paper

Experimental tractional retinal detachment in rabbits. Clinical picture and histopathologic features

Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology
M T TreseM O Hall

Abstract

A simple reproducible model for the creation of tractional retinal detachments in rabbits is presented. This model comprises retinal membranes composed of different cell types derived from ocular tissues, and eliminates the need for lengthy and expensive tissue culturing procedures. The injected cell bolus rapidly migrates to the optic disc and forms surface retinal membranes. These lead to tractional retinal detachment confined to the area of the vascular medullary rays. The rapidity and severity of the clinical process seems to be directly dependent upon the number of cells injected. Good visibility of the posterior pole is maintained throughout the course of the development of detachment. This model is acceptable for testing agents to suppress intraocular cellular proliferation. It can also serve to teach surgical techniques for the management of vitreo-retinal membranes without endangering human eyes.

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Citations

Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·N D RadtkeR J Ballou
Jan 1, 1986·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·W Behrens-Baumann, M Vogel
Jan 1, 1982·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·J M Burke, S J Foster
Oct 1, 1986·Experimental Eye Research·I GriersonD McLeod
Oct 1, 1982·American Journal of Ophthalmology·A OphirA J Claflin
May 1, 1982·American Journal of Ophthalmology·D M FastenbergS J Ryan
Jun 1, 1983·Acta Ophthalmologica·B Nicolaissen
Jan 13, 2021·Brain Research Bulletin·Zi-Yuan ZhangGuang-Yu Li

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