Experimental transfer of adult Oesophagostomum dentatum from donor to helminth naive recipient pigs: a methodological study

Journal of Helminthology
H BjørnP Nansen

Abstract

This study was carried out to compare potential methods of transplanting adult Oesophagostomum dentatum from experimentally infected donor pigs to helminth naive recipient pigs. The following methods were each tested in five pigs: A. Transfer of worms by stomach tube to the gastric ventricle of pigs per os pretreated with 0.5 mg/kg cisapride to increase gastrointestinal peristalsis; B. Transfer by stomach tube to the gastric ventricle of pigs per os pre-treated with cisapride (0.5 mg/kg) and omeprazol 20 mg which blocks hydrochloric acid secretion; C. Surgical transfer of worms to caecum of pigs. Worms for transplantation to pigs were obtained after slaughter of experimentally infected donor pigs and following isolation from the contents of the large intestine, using an agar gel migration technique. A mean of 1054 nematodes were transferred into each recipient pig within 2 hours. Procedures A and B resulted in establishment rates corresponding to only 0.5% and 7.6% of the transferred worms. In contrast, surgical transfer allowed 74.2% of the transplanted worms to be established. In all groups the transplanted worms migrated to the normal predilection site, i.e. the middle part of the large intestine. More female than male worms...Continue Reading

References

Apr 1, 1975·International Journal for Parasitology·R J Jorgensen
Apr 1, 1979·Parasitology·L F Le JambreP J Martin
May 1, 1987·Veterinary Parasitology·A RoepstorffP Nansen
Jun 1, 1986·Experimental Parasitology·N O ChristensenJ Andreassen
Sep 8, 1980·Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie·E B Bell

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